The editorial by Diamandis [1] in Janu-ary discussed a report by Walker et al. [2], who used strand displacement amplification and fluorescence polarization (FP) to detect Mycobacterium tuberculosis. The editorial placed particular emphasis on the homogeneous format of the assay. However, this aspect deserves to be expanded by an outline of the significance and evolution of combining DNA ampli-...

background and aim: otoacoustic emissions (oae) and automated auditory brainstem response (aabr) are the most commonly-used methods for universal neonatal hearing screening (unhs). various sensitivity and specificity rates have been reported for the oae and aabr tests as tools for screening newborn hearing. the main objective of this review was to determine the pooled sensitivity and pooled spe...

This document updates the colorectal cancer (CRC) when persons up to date with screening, who have prior screening recommendations of the U.S. Multi-Society Task Force of Colorectal Cancer (MSTF), which represents the American College of Gastroenterology, the American Gastroenterological Association, and The American Society for Gastrointestinal Endoscopy. CRC screening tests are ranked in 3 ti...

Screening tests are useful in a variety of settings and contexts, but not all disorders are amenable to screening. Alcohol use disorders (AUDs) and other drinking problems are a major cause of morbidity and mortality and are prevalent in the population; effective treatments are available, and patient outcome can be improved by early detection and intervention. Therefore, the use of screening te...

BACKGROUND The objective of the EUROCHIP project in Estonia was to describe the organized cervical cancer screening program started in 2006 (after pilot studies in 2003-2005), to compare its performance with opportunistic screening, and to define priorities for improvement of the program. METHODS Population data was retrieved from Statistics Estonia, data about performed Pap-smear tests withi...

Abstract Background Type 2 diabetes is a common non-communicable disease that responsible for about 9% of all deaths and 25% reduction in life expectancy. However, nearly half the diabetic patients are not aware their disease. In this regard, to identify un-known patients, screening great importance. This study was conducted evaluate performance two commonly used tests currently recommended by ...

BACKGROUND Little is known about how colorectal cancer screening test preferences operate together with test access and navigation to influence screening adherence in primary care. METHODS We analyzed data from a randomized trial of 945 primary care patients to assess the independent effects of screening test preference for fecal immunochemical test (FIT) or colonoscopy, mailed access to FIT ...

PURPOSE OF REVIEW The landscape of genetic diagnostic testing has changed dramatically with the introduction of next-generation clinical exome sequencing (CES), which provides an unbiased analysis of all protein-coding sequences in the roughly 21,000 genes in the human genome. Use of this testing, however, is currently limited in clinical neurologic practice by the lack of a framework for appro...