نتایج جستجو برای: shigellae
تعداد نتایج: 183 فیلتر نتایج به سال:
BACKGROUND Shigella infections are a public health problem in developing and transitional countries because of high transmissibility, severity of clinical disease, widespread antibiotic resistance and lack of a licensed vaccine. Whereas Shigellae are known to be transmitted primarily by direct fecal-oral contact and less commonly by contaminated food and water, the role of the housefly Musca do...
BACKGROUND & OBJECTIVES The resistance of enteropathogenic bacteria to commonly prescribed antibiotics is increasing both in developing as well as in developed countries. Resistance has emerged even to newer, more potent antimicrobial agents. The present study was therefore undertaken to report the current antibiotic resistance in common bacterial enteropathogens isolated in a tertiary care hos...
BACKGROUND Antimicrobial resistance is a major issue in the Shigellae, particularly as a specific multidrug-resistant (MDR) lineage of Shigella sonnei (lineage III) is becoming globally dominant. Ciprofloxacin is a recommended treatment for Shigella infections. However, ciprofloxacin-resistant S. sonnei are being increasingly isolated in Asia and sporadically reported on other continents. We hy...
Shigella is a major cause of morbidity, mortality, and growth retardation for children in developing countries. Emergence of antibiotic resistance among Shigellae demands the development of effective medicines. Previous studies found that the endogenous antimicrobial peptide LL-37 is down-regulated in the rectal epithelium of patients during shigellosis and that butyrate up-regulates the expres...
SIR—We read with great interest the report by Raguin et al. [1] on Shigella boydii as a possible causative agent of colonic malacoplakia in an HIV-infected patient. In the absence of positive cultures, S. boydii was identified by means of universal bacterial 16S rDNA–based amplification and sequencing. Since malacoplakia is usually caused by Escherichia coli, a close relative of shigellae and g...
The genetic determinants required for invasion of epithelial cells by Shigella flexneri and for the subsequent bacterial spreading are encoded by the large virulence plasmid. Expression of the virulence genes is under the control of various genes on the large plasmid as well as on the chromosome. We previously identified one of the virulence-associated loci near phoBR in the NotI-C fragment of ...
Clinical Microbiology is a very applied science, trying all the while to use any or all scientific techniques to achieve a very specific purpose: the rapid and accurate diagnosis of infections and infectious diseases. To this end, Clinical Microbiologists have quite unashamedly begged, stolen or borrowed methods and applications from anyone else! This endless plagiarism has left obvious footpri...
Because of the great demand for bacteriological examination of faecal specimens for Salmonella and Shigella organisms, there is need for a simplified biochemical method of preliminary differentiation of the Enterobacteriaceae to replace the widely used differential set of sugars involving inoculation of six or more tubes of separate media. The basic requirements of such a method are that it sho...
Straight cylindrical rods, 1.1–1.5 " 2.0–6.0 lm, occurring singly or in pairs. Conform to the general definition of the family Enterobacteriaceae. Gram negative. Motile by peritrichous flagella or nonmotile. Aerobic and facultatively anaerobic having both a respiratory and a fermentative type of metabolism, but anaerogenic biotypes occur. Oxidase negative. Chemoorganotrophic. Both acid and gas ...
Demerec (1945) and Luria (1946), in studying the resistance of staphylococci to penicillin, found that for a given inoculum (approximately 300,000,000 bacteria) there was a variation in resistance of approximately tenfold for all of their strains; e.g., if the inoculum required 0.1 unit of penicillin for complete inhibition, many of the bacteria in the inoculum would be inhibited by as little a...
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