BACKGROUND Since the introduction of sentinel lymph node biopsy (SLNB), its use as a standard of care for patients with clinically node-negative cutaneous melanoma remains controversial. We wished to evaluate our experience of SLNB for melanoma. METHODS A single center observational cohort of 203 melanoma patients with a primary cutaneous melanoma (tumour thickness > 1 mm) and without clinica...

AIM OF THE STUDY To determine the feasibility of sentinel lymph node biopsy (SLNB) for the evaluation of the cervical lymph node status in patients with thyroid tumors. MATERIAL AND METHODS Twenty-three patients with suspected thyroid cancer were enrolled in the study. 0.5-1.0 ml of 1% Patent Blue dye was injected intratumorally. After SLNB, thyroidectomy and proper lymphadenectomy were perfo...

Objective: Evaluation of the pathological status of the pelvic lymph nodes (LNs) is the most important prognostic factor of recurrence and survival in early -stage cervical cancer. Radical hysterectomy and pelvic lymphadenectomy is the cornerstone treatment of cervical cancer, however the morbidity rate associated with pelvic LN dissection is significantly high. Applying the Sentinel LN (SLN) c...

BACKGROUND Axillary reverse mapping (ARM) is a new technique to preserve upper extremity lymphatic pathways during axillary lymph node dissection (ALND), thereby preventing lymphedema patients with breast cancer. However, the oncologic safety of sparing the nodes identified by ARM (ARM nodes), some of which are positive, has not been verified. We evaluated the metastatic status of ARM nodes and...

Current international recommendations are to omit sentinel lymph node biopsy (SLNB) in cT1N0 HR+ older breast cancer patients. Symptomatic cancers customarily more aggressive than screen-detected.

Targeted axillary dissection (TAD) is a new staging technique that consists of the surgical removal biopsy-proven positive nodes, which are marked (marked lymph node biopsy (MLNB)) prior to neoadjuvant chemotherapy (NACT) in addition sentinel (SLNB). In meta-analysis more than 3000 patients, we previously reported false-negative rate (FNR) 13% using SLNB alone this setting. The aim systematic r...

Sentinel lymph node biopsy (SLNB) has emerged as an alternative to axillary dissection during breast cancer surgery the last 2 decades. However, there are several controversies regarding indication of sentinel after neoadjuvant chemotherapy which can convert positive nodes negative. The false-negative rate is unacceptably high. This high be decreased by marking and removal procedure in addition...

The objective of this study was to conduct a systematic review and meta-analysis on the efficacy sentinel lymph node biopsy (SLNB) in T1/T2-N0 oral squamous cell carcinoma (OSCC). A literature SLNB until March 2019 conducted. organized according PRISMA protocol, considering following PICO (population, intervention, comparison, outcome) question: What is sensitivity OSCC? ‘P’ patients with head ...

Introduction: National guidelines for cutaneous melanoma suggest avoiding sentinel lymph node biopsy (SLNB) if the risk of SLN positivity is <5% (T1a with no high-risk features), considering SLNB 5-10% additional features (T1aHR) and T1b), offering >10% (T2-T4). Because most patients (88%) who undergo an have a negative result, novel tools to identify can safely forgo are critical. The in...