Background: Adult degenerative disorders of hip and spine are common. The recent studies inconsistently havediscussed about the influence of spinal disorders on total hip arthroplasty (THA). In this review, we discussed clearlyabout these relationships and their effects on the most appropriate position of the acetabular component.Methods: We searched on databases and evaluated the articles abou...

background: early warning of potential damage to spinal cord during major spinal surgery is highly desirable to prevent post-operative neurological deficits. wake-up test is a simple, safe and reliable method of recognition of such a complication, and has been extensively used in many spinal surgical units. the present study is evaluating the remifentanil, propofol versus alfentanil, propofol a...

in worldwide, an estimated 40 cases per 1 million people reported with new spinal cord injuries each year. people with spinal cord injuries suffer from severe physical, psychological, social and economic problems. damaged or lost cells can't be replaced when the spinal cord is injured; therefore, its function becomes disturbed permanently. despite the significant advances in the understand...

conclusions administration of two different doses of intravenous ondansetron, 6 mg and 12 mg, significantly attenuates spinal induced hypotension, bradycardia and shivering compared to the control saline group. however, the hemodynamic profiles and shivering in experimental groups were not statistically different. results demographic data were not statistically different among groups. hr was st...

background spinal anesthesia is an important and commonly used method for surgical anesthetic in operating rooms. however, even with identical drug dosage and administration mode, the extent of drug distribution in vivo is highly variable and difficult to control. preanesthetic administration of fluids immediately before spinal anesthesia (preload) is normal practice. the choice of fluid type m...

spinal muscular atrophy (sma) is a genetic disorder which affect nervous system and is characterized with progressive distal motor neuron weakness. the survival motor neuron (smn) protein level reduces in patients with sma. two different genes code survival motor neuron protein in human genome. skeletal and intercostal muscles denervation lead to weakness, hypotony, hyporeflexia, respiratory fa...

stem cell therapy can be useful for spinal cord injury (sci). induced pluripotent stem cells (ipscs) are generated by reprogramming mature, fully differentiated cells into a pluripotent state. the ability to generate pluripotent cells from adult somatic cells without the need for an embryo was a major development in stem cell biology. ipscs were established from mouse fibroblasts and demonstrat...

objective(s) recent studies revealed the neuroprotective effects of epigallocatechin gallate (egcg) on a variety of neural injury .the purpose of this study was to determine the effects of egcg on the tissue lipid peroxidation after spinal cord injury (sci). materials and methods rats were randomly divided into four groups of 7 rats each as follows: sham-operated group, trauma group, and egcg-t...