BACKGROUND Laparoscopic splenectomy has become an important therapeutic option in the management of diverse hematologic disorders. However, the incidence of important complications, such as portal vein thrombosis, remains poorly understood. We set out to study the incidence of this complication over a 14-month period. METHODS All adult patients who underwent laparoscopic splenectomy between J...

BACKGROUND A considerable number of patients with portal hypertension (PHT) have to undergo splenectomy because they do not meet the requirements for liver transplantation (LT) or cannot find a suitable liver donor. However, it is not known whether pre-transplantation splenectomy may create occult difficulties for patients who require LT in future. METHODS We analyzed 1059 consecutive patient...

OBJECTIVE To document the existence of residual splenic function after laparoscopic splenectomy in a series of 48 patients. DESIGN A noncomparative descriptive case series. SETTING A tertiary care center. PATIENTS A series of 9 patients without clinical improvement after laparoscopic splenectomy of 48 consecutive patients undergoing laparoscopic splenectomy for several hematologic disorde...

HYPOTHESIS Splenic-preserving distal pancreatectomy for benign or low-grade malignant disease is associated with decreased perioperative morbidity compared with conventional distal pancreatectomy with splenectomy. DESIGN A retrospective review of a prospective database of patients. SETTING Memorial Sloan-Kettering Cancer Center, New York, NY. PATIENTS All patients (N = 211) undergoing dis...

BACKGROUND The spleen is amongst the most vulnerable organs which are easily injured in abdominal trauma. Nowadays, blunt trauma is the most prevalent indication of splenectomy. OBJECTIVES We conducted this study to determine the pattern of indications for open splenectomies carried out during the past five years in Shahid-Beheshti hospital, a central hospital in Kashan, Iran. PATIENTS AND ...

UNLABELLED Despite the growing understanding of the pathophysiological processes in the perioperative period and significant advancements in surgical techniques, operative treatment for gastric cancer remains a challenge for surgeons, especially because the primary procedure of total or nearly total gastrectomy must at times be extended by the resection of other organs. The aim of the study was...

The treatment of choice in steroid-resistant immune thrombocytopenia is still controversial due to the recent advent of new drugs (anti-CD20 antibodies and thrombopoietin mimetics) that have encouraged a generalized tendency to delay splenectomy. Consequently, it is extremely importance to define the efficacy and safety of splenectomy in the long term. We retrospectively analyzed the data of 23...

AIM To assess the results of supportive treatment with intravenous immunoglobulin (IVIG) and antibiotic prophylaxis in combination with splenectomy in patients with Wiskott-Aldrich syndrome. STUDY DESIGN Retrospective review of case records of 21 patients from March 1984 to February 1996. RESULTS Thrombocytopenia was cured in 14 of 15 patients who had splenectomy, but it recurred intermitte...

OBJECTIVES Laparoscopic splenectomy has been increasingly used in patients with idiopathic thrombocytopenic purpura. Because it is associated with minimal abdominal trauma, platelet consumption could be reduced with the laparoscopic approach. The aim of this study was to analyze intraoperative bleeding and the need for apheresis platelets, comparing laparoscopic with open splenectomy. METHODS...

H EREDITARY SPHEROCYTOSIS is characterized by the occurrence of a hemolytic anemia in at least two family members, the presence of spherocytes in the peripheral blood, increased osmotic fragilities of fresh and incubated blood, an increased autohemolysis partially corrected by supplementary glucose and complete clinical remission following splenectomy. Several cases lacking one of these major f...