Abstract Aim To describe the demographics of a large general practices post-splenectomy patient population (including sex, age, and indication for splenectomy), audit cohort's care against national immunisation antibiotic prophylaxis guidelines. Method All adult patients registered with practice who had undergone surgical splenectomy were included. Included patients’ medical records reviewed da...

BACKGROUND The spleen is an active lymphoid organ. The effect of splenectomy on the immune response remains unclear. This study investigated whether splenectomy can induce immune tolerance and has a beneficial role in cardiac allograft. METHODS Wistar rats were used for heart donors. The Sprague-Dawley (SD) rats designated as the recipients of heart transplantation (HT) were randomly assigned...

BACKGROUND AND OBJECTIVES Laparoscopic splenectomy for massive splenomegaly is still a controversial procedure as compared with open splenectomy. We aimed to compare the feasibility of laparoscopic splenectomy versus open splenectomy for massive splenomegaly from different surgical aspects in children. METHODS The data of children aged <12 years with massive splenomegaly who underwent splenec...

Objective- To assess the feasibility of splenectomy using intracorporeal ligature placement technique. Design- Randomized experimental study. Animals- Dogs (n=7) weighting≥ 20 kg. Procedures- Dogs were randomly selected. A lap-assisted splenectomy was performed. The feasibility of splenectomy was examined using intracorporeal ligatures. Comparisons were made regarding the anes...

spleen is a major component of the reticuloendothelial system and functions as a filtering system for the encapsulated bacteria especially in children. knowing the spectrum of conditions leading to splenectomy in any geographic area is important to decrease the number of unnessesary splenectomies. here we report the causes of splenectomy in three major general referring hospitals in shiraz, the...

a rare case of splenic harmartoma in a 31 year old female is reported. she was admitted with splenomegaly, fever and chronic history of epistaxis. routine hematological survey revealed pancytopenia and mild hypercellular marrow. abdominal sonography showed a space-occupying lesion in the spleen which was suspected as malignant tumor. splenectomy was performed and histologic findings were diagno...

OBJECTIVES Little is known about the risk of pyogenic liver abscess in patients with splenectomy. We explored the relationship between splenectomy and pyogenic liver abscess in Taiwan. METHODS We conducted a nationwide cohort analysis using the hospitalization dataset of the Taiwan National Health Insurance Program. We included 17,779 subjects aged 20-84 years who underwent splenectomy in 199...

OBJECTIVE This study aimed to investigate the association between splenectomy and empyema in Taiwan. METHODS A population-based cohort study was conducted using the hospitalisation dataset of the Taiwan National Health Insurance Program. A total of 13 193 subjects aged 20-84 years who were newly diagnosed with splenectomy from 2000 to 2010 were enrolled in the splenectomy group and 52 464 ran...

Laparoscopic splenectomy (LS) has become an established standard of care in the management of surgical diseases of the spleen. The present article is an update and review of current procedures and controversies regarding minimally invasive splenectomy. We review the indications and contraindications for LS as well as preoperative considerations. An individual assessment of the procedures and ou...