نتایج جستجو برای: str haplotyping
تعداد نتایج: 6432 فیلتر نتایج به سال:
توالی های تکراری پی درپی (tandem repeats) از اهمیت بالایی در ژنتیک انسانی برخوردارند و در این میان توالی های تکراری کوتاه (strها) امروزه اهمیت بسیار شایان توجهی در بررسی های ژنتیک انسانی و تشخیص هویت در پزشکی قانونی دارند. تعداد بسیار زیادی از این توالی ها در سرتاسر ژنوم انسانی پراکنده اند که دارای توالی های تکراری با طول مختلف و تعداد تکرارهای مختلف هستند. لیکن امروزه تحقیقات نشان داده است که ...
Determining the underlying haplotypes of individual human genomes is an essential, but currently difficult, step toward a complete understanding of genome function. Fosmid pool-based next-generation sequencing allows genome-wide generation of 40-kb haploid DNA segments, which can be phased into contiguous molecular haplotypes computationally by Single Individual Haplotyping (SIH). Many SIH algo...
Second generation sequencing (SGS) may revolutionize the field of forensic STR typing. Two of the essential requirements for implementation of an SGS based approach for forensic investigations are (1) establishment of adequate frequency databases and (2) adoption of a new STR nomenclature. We report the STR sequences and allele frequencies of three STR loci: D3S1358, D12S391 and D21S11 in 197 u...
Short tandem repeats (STRs) are highly mutable genetic elements that often reside in regulatory and coding DNA. The cumulative evidence of genetic studies on individual STRs suggests that STR variation profoundly affects phenotype and contributes to trait heritability. Despite recent advances in sequencing technology, STR variation has remained largely inaccessible across many individuals compa...
ELENA MIHAELA CARAUSU1, VIOLETA TRANDAFIR2,3*, LAURA GHIBU4,5*, OVIDIU STAMATIN6, LAURA ELISABETA CHECHERITA7 1Grigore T. Popa University of Medicine and Pharmacy, Faculty of Dental Medicine, Department of Management and Public Health Dentistry, 16 Universitatii Str, 700115, Iasi, Romania 2 Grigore T. Popa University of Medicine and Pharmacy, Faculty of Dental Medicine, Department of Oral and M...
This paper presents the development of a Genetic Algorithm Supervisory Loop (GASL) to enhance the performance of Adaptive Controllers in the Self Tuning Regulator (STR) framework. The GASL is designed to tune the identification model and control parameters to achieve an optimum performance of the process. The STR controller used to demonstrate the technique effectiveness is a real time Proporti...
FELICIA DRAGAN1, IRINA KACSO2, FLAVIA MARTIN2*, GHEORGHE BORODI2, IOAN BRATU2, MARCEL COSTULEANU3, IOAN GABRIEL SANDU4,5*, VLADIMIR POROCH6,7 1 Oradea University, Faculty of Medicine and Pharmacy, 1 Armatei Romane Str., 410087, Oradea, Romania 2 National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Str., 400293, Cluj Napoca, Romania, 3 Grigore T. P...
In this study, we report that the treatment of strychinine (STR), an inhibitor of glycine receptor, induced premature onset of programmed cell death (PCD) of developing chick motoneurons (MNs). Treatment of STR on E4 chick embryo increased the apoptosis of MN on E5 when MN PCD does not occur normally. On the other hand, treatment of STR from E3 or E5 for 24 hours did not significantly influence...
We introduce Space-Time Routing (STR), a new approach to routing in mobile ad hoc networks. In STR, the age of routing state is considered jointly with the distance to the destination. We give a general description of STR, which can accommodate various temporal (age) and spatial (distance) metrics. Our formulation of STR describes a family of routing algorithms, parameterized by a choice of nod...
CoAuthors: 1. Nikolaos Smyrnis, MD Aeginition Hospital, 72 Vas. Sofias Ave,11528, Athens, Greece 2. Anastasios Dimoliatis MLT 61 Mainandrou str. Ilioupoli, 3. Brig Gen (ret.) Christos Daskalopoulos, MD 18 Siokou str. Agia Paraskeui, 15341, Athens Greece 4. Lt Col Konstantinos Giatas, MD 251 Hellenic Air Force General Hospital, 3 P. Kanelopoulou Str. Cholargos, 11525, Athens , Greece 5. Major An...
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