نتایج جستجو برای: stromal desmoplasia

تعداد نتایج: 42929  

Journal: :iranian biomedical journal 0
مهدی نیکبخت دستجردی mehdi nikbakht dastjerdi

background: silk fibroin is a suitable protein for osteogenesis by inducing markers of bone formation in the cultures of osteoblasts, so we examined the ability of this protein to induce mineralized nodules in the rat bone marrow stromal cell cultures. methods: bone marrow stromal cells obtained from 4 to 6 weeks old spruge-dawely male rats were grown in primary culture for seven days and then ...

Journal: :cell journal 0

introduction: there are the evidences to suggest that bone marrow stromal cells (bmscs) not only differentiate into mesodermal cells, but also adopt the fate of endodermal and ectodermal cell types. bmscs can be a valuable cell source as an autograph for clinical application involving regeneration of the central nervous system. bone marrow stromal cells can be expanded rapidly in vitro and have...

2015
Dario Garcia-Carracedo Chih-Chieh Yu Nathan Akhavan Stuart A. Fine Frank Schönleben Naoki Maehara Dillon C. Karg Chuangao Xie Wanglong Qiu Robert L. Fine Helen E. Remotti Gloria H. Su

AIMS While overexpression of TGFα has been reported in human pancreatic ductal adenocarcinoma (PDAC), mice with overexpressed TGFα develop premalignant pancreatic acinar-to-ductal metaplasia (ADM) but not PDAC. TGF-β signaling pathway is pivotal to the development of PDAC and tissue fibrosis. Here we sought to investigate the interplay between TGFα and TGF-β signaling in pancreatic tumorigenesi...

Journal: :medical journal of islamic republic of iran 0
soheila aminimoghaddam department of gynecology, firoozgar hospital, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)سازمان های دیگر: firoozgar hospital atefeh-sadat ebrahimi department of gynecology, firoozgar hospital, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)سازمان های دیگر: firoozgar hospital forough hashemi department of pathology, firoozgar hospital, tehran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)سازمان های دیگر: firoozgar hospital

leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. they produce testosterone leading to hyperandrogenism. we present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra sonography, and a rise of total and free serum testosterone. an ovarian source of androgen was suspected and a surgery performed. a diagnosis o...

2016
Jeremy Chen Don J. Diamond Edwin R. Manuel

Pancreatic ductal adenocarcinoma (PDAC) is predicted to have the second highest incidence of fatalities among all solid tumor malignancies worldwide. Despite three decades of research focused on treating PDAC, the five-year survival rate is less than 6%, thus leaving much room for improvement. Historically, PDAC has been difficult to treat due to the absence of early detection methods resulting...

Ghanbari A Ghorbani R Khazaei M, Lotfi Kangarshahi R, Rashidi Z

Background: Noscapine is a water soluble alkaloid with antitussive property and very less toxicity. It is obtained from the Papaveraceae family. Recently, new pharmacological properties such as anticancer, anti stroke and anti-angiogenic effects are introduced. There is no scientific report on noscapine effect on reproductive system. The aim of present study was to determine in vitro effect of ...

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