The organization of alpha-globin genes in normal white European, normal Algerian, and alpha-thalassemic Algerian DNA was examined by restriction endonuclease mapping using HindIII, HpaI, Bamhi, EcoRI, BgIII, and PstI. The results for normal DNA confirm and add to the findings of Surrey et al. and Orkin; the two alpha-genes are approximately 3.0 kb apart. The restriction enzymes BgIII and HpaL c...

Most α-thalassemia cases are caused by deletions of the structural α-globin genes. The degree of microcytosis and hypochromia has been correlated with the number of affected α-globin genes, suggesting a promising role of hematologic parameters as predictive diagnostic tools. However, cut-off points for these parameters to discriminate between the different subtypes of α-thalassemia are yet to b...

The orbital instability of ground state standing waves eφω(x) for the nonlinear Klein-Gordon equation has been known in the domain of all frequencies ω for the supercritical case and for frequencies strictly less than a critical frequency ωc in the subcritical case. We prove the strong instability of ground state standing waves for the entire domain above. For the case when the frequency is equ...

conclusions based on this similarity and our bioinformatics evaluations, this mentioned alpha-amylase gene can be expressed in s. cerevisiae as extracellular enzyme. results the presence of alpha-amylase gene in recombinant bacteria was certificated by colony-pcr method. after extraction of recombinant vector from e. coli, the competent s. cerevisiae cells were transformed using polyethylene gl...

OBJECTIVES Parkinson's disease is one of the most common neurodegenerative diseases in the elderly population. In order to estimate the prevalence of Parkinson's disease in the community, the application of a good screening tool is essential. We evaluated the validity and reliability of a Parkinson's disease screening questionnaire and propose an alternative measure to improve its validity for ...

introduction: nowadays, due to mechanization of life, consumers need of food which they spent little time for preparation, so fresh cut industry is growing rapidly in the world. these products had strong growth since 1940, and in 2013, most sales of fresh cut fruit related to apples, against 21.8 percent. minimal processing operations include grading, washing, sorting, slicing, chopping and the...

BACKGROUND Simpson-Angus Scale (SAS) is an established instrument for neuroleptic-induced parkinsonism (NIP), but its statistical properties have been studied insufficiently. Some shortcomings concerning its content have been suggested as well. According to a recent report, the widely used SAS mean score cut-off value 0.3 of for NIP detection may be too low. Our aim was to evaluate SAS against ...

<p>We elaborate in this paper a new structure Pythagorean fuzzy<br />$N$-soft groups which is the generalization of intuitionistic />soft group initiated by Karaaslan 2013. In />N-soft sets concepts fuzzy sets, soft N-soft soft<br />sets, are<br />generalized. We also talk about some elementary basic and<br />operations on with assistance of<br />illusi...

An inventory model is formulated with type-2 fuzzy parameters under trade credit policy and solved by using Generalized Hukuhara derivative approach. Representing demand parameter of each expert's opinion is a membership function of type-1 and thus, this membership function again becomes fuzzy. The final opinion of all experts is expressed by a type-2 fuzzy variable. For this present problem, t...

BACKGROUND It is thought that depressive disorders will be the second leading cause of disability worldwide by 2020. Recently, there is a steady increase in the number of university students diagnosed and treated as depression patients. It can be assumed that depression is a serious mental health problem for university students because it affects all age groups of the students either younger or...