BACKGROUND We examined the implications of iNOS in atherosclerosis progression using the selective inducible NO synthase (iNOS) inhibitor N:-iminoethyl-L-lysine (L-NIL) in hypercholesterolemic rabbits. METHODS AND RESULTS Nine rabbits were fed a 0.3% cholesterol diet for 24 weeks (Baseline group); 25 animals were maintained on the diet and treated for 12 extra weeks with L-NIL (5 mg x kg(-1) ...

Near-infrared light (NIL) promotes a wide range of biological effects including enhancement of energy production, gene expression and prevention of cell death. This is the first report of the in vivo neuroprotective effects of NIL against optic neuropathy induced by mitochondrial complex I inhibition. Subjects were pigmented rats that received single bilateral intravitreal doses of rotenone, a ...

The adjacency matrix of a graph can be interpreted as the incidence matrix of a design, or as the generator matrix of a binary code. Here these relations play a central role. We consider graphs for which the corresponding design is a (symmetric) block design or (group) divisible design. Such graphs are strongly regular (in case of a block design) or very similar to a strongly regular graph (in ...

Explicit expressions for the second order statistics of cepstral components representing clean and noisy signal waveforms are derived. The noise is assumed additive to the signal, and the spectral components of each process are assumed statistically independent complex Gaussian random variables. The key result developed here is an explicit expression for the cross-covariance between the log-spe...

In this paper we continue developing the theory of symplectic alternating algebras that was started in [3]. We focus on nilpotency, solubility and nil-algebras. We show in particular that symplectic alternating nil-2 algebras are always nilpotent and classify all nil-algebras of dimension up to 8.

The present study elucidated the effect of the selective inducible nitric oxide synthase (iNOS) inhibitor N(6)-(1-iminoethyl)-L-lysine (L-NIL) on monosodium urate (MSU) crystal-induced inflammation and edema in mice feet. L-NIL (5 or 10 mg/kg/day) was administered intraperitoneally 4 h before injection of MSU (4 mg) into the soles of mice hindlimb feet. Twenty-four hours after MSU injection, fo...

introduction: ischemia/reperfusion (ir) injury involves a complex interrelated sequence of events. high levels of nitric oxide (no) are generated with inducible form of nitric oxide synthase (inos) leading to the renal ir injury and glutathione (gsh) depletion. the present study was designed to investigate the effect of l-nil (n6- (1-iminoethyl)-l- lysine.hydrochloride), a selective inhibitor o...

BACKGROUND Fusarium head blight (FHB), mainly caused by Fusarium graminearum, substantially reduces wheat grain yield and quality worldwide. Proteins play important roles in defense against the fungal infection. This study characterized differentially expressed proteins between near-isogenic lines (NILs) contrasting in alleles of Fhb1, a major FHB resistance gene in wheat, to identify proteins ...