A moderate increase in physical activity and a detailed and tailored Mediterranean-style diet reduce the prevalence of metabolic syndrome and associated cardiovascular risks through reducing systemic vascular inflammation and endothelium dysfunction, particularly in those patients who do not lose weight.

Patients who suffer from severe burns develop metabolic imbalances and systemic inflammatory response syndrome (SIRS) which can result in multiple organ failure and death. Research aimed at reducing the inflammatory process has yielded new insight into burn injury therapies. In this review, we discuss strategies used to curb inflammation in burn injuries and note that further studies with high ...

Introduction Macrophage activation syndrome (MAS) is a lifethreatening complication of childhood systemic inflammatory disorders. HMGB1 is a nuclear protein that extracellularly orchestrates key events in inflammation. Recent data revealed that different redox states of three cysteines within HMGB1 render it with mutually exclusive activities: reduced all-thiol-HMGB1 exerts chemotactic activity...

Background: In the elderly population joint swelling, effusion and pain indicate local synovitis and the presence of inflammation. At present, no serum marker has been shown linking to knee synovitis in KOA. With regard to serum high sensitive C-reactive protein (hsCRP) as a measure of inflammation, this study aimed to determine the association of systemic inflammation with local synovitis, as ...

Churg-Strauss syndrome is a rare systemic vasculitis occurring in patients with asthma and blood eosinophilia. Lungs, skin, and nervous system are the most common sites of involvement, although many other organs are affected frequently. The diagnosis often is established from clinical findings or biopsy of extrapulmonary sites, and lung biopsy is performed infrequently. The classic pathologic f...

Introduction: Metabolic syndrome, a constellation of features such as obesity, hypertension, dyslipidemia and insulin resistance is common occurrence in patients with psoriasis. Systemic inflammation supposed to play significant role both conditions. The co-occurrence metabolic syndrome psoriasis can result clinical consequences. aim this study was find out the prevalence among attending Outpat...

BACKGROUND The role of inflammation, vascular dysfunction and oxidative stress in the pathophysiology of different stroke subtypes is not well understood. We aimed to determine if the clinical and aetiologic subtype of acute ischaemic stroke influences systemic markers of vascular function, inflammation and oxidative stress. MATERIAL/METHODS 129 men and women were recruited within 10 days of ...

BACKGROUND The role of inflammation in patients with coronary artery disease is emerging. We sought to assess the profile and outcomes of patients with a clinical syndrome of severe systemic inflammation that led to a diagnosis of suspected sepsis in the setting of acute myocardial infarction complicated by cardiogenic shock (CS). METHODS Patients enrolled in the randomized SHOCK (SHould we e...