نتایج جستجو برای: thiotcpa t group and thiotepa cetrorelix

تعداد نتایج: 17021395  

Azami A Mohammadnejad D Nikpour F Tayefi Nasrabadie H

Background: Male factors, mainly spermatogenesis disorder, are responsible for 20-30% of infertility occurs in different societies. One of the known causes of spermatogenesis disorder is chemotherapy in patients with cancer. The side effect of chemotherapic agents may last from 10 years up to the end of the life. Since dividing cells are mainly affected by anticancer drugs, the aim of the prese...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Milly E de Jonge Alwin D R Huitema Annemarie C Tukker Selma M van Dam Sjoerd Rodenhuis Jos H Beijnen

PURPOSE Relationships between toxicity and pharmacokinetics have been shown for cyclophosphamide, thiotepa, and carboplatin (CTC) in high-dose chemotherapy. We prospectively evaluated whether variability in exposure to CTC and their activated metabolites can be decreased with pharmacokinetically guided dose administration and evaluated its clinical effect. EXPERIMENTAL DESIGN Patients receive...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Judit E Horvath Ana M Bajo Andrew V Schally Magdolna Kovacs Francine Herbert Kate Groot

The effects of depot formulations of the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl (25 microg/day) for 30 days or LHRH antagonist Cetrorelix pamoate (100 microg/day) for 30 days and daily injections of 100 microg of Decapeptyl for 10 days on the expression of mRNA for pituitary LHRH receptor (LHRH-R) and the levels of LHRH-R protein were evaluated in rats. Serum sex steroi...

2015
Anita Kåss Ivana Hollan Morten Wang Fagerland Hans Christian Gulseth Peter Abusdal Torjesen Øystein Torleiv Førre Cornelis B Lambalk

OBJECTIVES Gonadotropin-releasing hormone (GnRH) and pituitary gonadotropins, which appear to be proinflammatory, undergo profound secretory changes during events associated with rheumatoid arthritis (RA) onset, flares, or improvement e.g. menopausal transition, postpartum, or pregnancy. Potential anti-inflammatory effects of GnRH-antagonists may be most pronounced in patients with high GnRH an...

Nikpour F, Soleimani Rad J

Background: Male factors, mainly spermatogenesis disorder, are responsible for 20-30% of infertility occurred in different societies. One of the known causes of spermatogenesis disorder is chemotherapy in patients with cancer. The side effect of chemotherapic agents may last from 10 years up to the end of the life. Since dividing cells are mainly affected by anticancer drugs, the aim of the pre...

Journal: :British Journal of Haematology 2021

The worldwide incidence of multiple myeloma (MM) has been rising continuously, representing an overall increase 126% from 1990 to 2016 in almost all regions, regardless socio-demographic status and availability sensitive diagnostic techniques.1 Though remarkable progress made, the disease is still currently incurable. Nearly 13% patients will develop extramedullary due natural accumulation muta...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان همدان - دانشکده ادبیات و علوم انسانی 1390

abstract this study is an attempt to determine the effect of nano- technology education on science lesson for fifth grade in primary school in the city of kermanshah. this research is experimental and is conducted in the from of pre-test and post- test for the control group. an achievement test was administered to determine the rate of learning in the students. the research is an applied one. ...

Journal: :Reproductive BioMedicine Online 2002

پایان نامه :موسسه آموزش عالی غیردولتی رودکی تنکابن - دانشکده ادبیات و علوم انسانی 1394

this study was conducted to investigate the effect of favorite-text on iranian intermediate efl learners’ vocabulary development. sixty learners from nour-al-mahdi english institute participated in the present study. having been homogenized by oxford placement test (opt), they were randomly assigned into two groups of 30, control and experimental. then both groups sat for a pre-test which was a...

Journal: :Scientific reports 2015
Qingkun Song Xinna Zhou Jing Yu Ningning Dong Xiaoli Wang Huabing Yang Jun Ren H Kim Lyerly

This study investigated interactive effects of CYP2B6 genotypes and liver metastasis on the prognosis of metastatic breast cancer patients who received combined chemotherapy of docetaxel and thiotepa. Totally 153 patients were retrospectively genotyped rs8192719 (c.1294 + 53C > T) and rs2279343 (c.785A > G). Kaplan-Meier method and Cox Proportional Hazard Regression model were used to estimate ...

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