Gene expression microarrays have been the vanguard of new analytic approaches in high-dimensional biology. Draft sequences of several genomes coupled with new technologies allow study of the influences and responses of entire genomes rather than isolated genes. This has opened a new realm of highly dimensional biology where questions involve multiplicity at unprecedented scales: thousands of ge...

Hacı Bektaş Veli is a person who had important effects on the formation of religious and mystical thought Anatolia. Understanding his ṣūfī mission for analyzing Turkish- Islamic thought. The concept maʿrifa (interior knowledge) forms basis Bektaş’s In this context, present study focuses emphasis adherence to Sharia way in thought, sect maqāms obtained with implementation Sharia, then heart as m...

Some studies have found that trying to suppress thoughts increases their long-term recurrence, a phenomenon associated with psychopathology, particularly obsessive-compulsive disorder. However, effect sizes in thought suppression studies have often been small and inconsistent. The present study sought to improve thought suppression conceptualization and measurement by examining two distinct dim...

BACKGROUND The multi-arm multi-stage (MAMS) design described by Royston et al. [Stat Med. 2003;22(14):2239-56 and Trials. 2011;12:81] can accelerate treatment evaluation by comparing multiple treatments with a control in a single trial and stopping recruitment to arms not showing sufficient promise during the course of the study. To increase efficiency further, interim assessments can be based ...

For many years, subset analysis has been a popular topic for the biostatistics and clinical trials literature. In more recent years, the discussion has focused on finding subsets of genomes which play a role in the effect of treatment, often referred to as stratified or personalized medicine. Though highly sought after, methods for detecting subsets with altering treatment effects are limited a...

At least since Gabriel (1969), a broad class of multiple comparison procedures, socalled simultaneous test procedures (STPs), is established in the statistical literature. Elements of an STP are a testing family (H, T ), consisting of a set of null hypotheses and corresponding test statistics, and a common critical constant cα. The threshold cα with which each of the test statistics has to be c...

INTRODUCTION The duration of human pregnancy is arbitrarily taken as 280 days (40 weeks). Foetuses are considered to be at high risk once pregnancy goes beyond the expected date of confinement. This study was carried out with the aim of determining the mean gestation age of low-risk pregnancies that went into spontaneous labour and the incidence of adverse outcomes in relation to gestation. M...