TH(AGYLLGHINLHHLAHL(Aib)HHIL-NH2), a histidine-rich, cell-penetrating peptide with acid-activated pH response, designed and synthesized by our group, can effectively target tumor tissues with an acidic extracellular environment. Since the protonating effect of histidine plays a critical role in the acid-activated, cell-penetrating ability of TH, we designed a series of new histidine substituent...

'… if we could successfully intervene and change a woman's age at first birth and n oth in g else about her up to that point'? 1 Scally argu es th at we do n ot deal with th e m u ch m ore im port-an t issu es of th e edu cation al an d social effects of early m oth er-h ood an d focu s on a n arrow m edical defin ition of pu blic h ealth. We wou ld argu e th at we deal prim arily with th e det...

Polypyrrole magnetic graphene oxide (PPy/MGO) composites have been synthesized from a natural source (water hyacinth roots) using polymerization technique for Th(IV) ions pre-concentration from aqueous solutions. The effects of controlling factor have been studied using the batch technique. The obtained results show that the maximum Th(IV) adsorption capacity by PPy/MGO composite is 277.8 m...

Extraction-separation of Eu(III) and Th(IV) ions from nitrate media into the ionic liquid 1-hexyl-3-methylimidazolium hexafluorophosphate by a phosphorylated salen extractant, bis(chlorophosphoryle)decahydro-2,4-di(2-hydroxyphenyl)benzo[d][1,3,6]oxadiazepine (DPO), is investigated. It is found that Eu(III) ions are extracted via a solvation mechanism, and the extraction of Th(IV) i...

BACKGROUND Newer dentin bonding agents were developed to improve the quality of composite restoration and to reduce time consumption in its application. The aim of the present study was to evaluate tensile bond strength of 6(th), 7(th) and 8(th) generation bonding agents by in vitro method. MATERIALS AND METHODS Selected 60 permanent teeth were assigned into 20 in each group (Group I: 6(th) g...

background: coronary heart disease is one of the most important problems of public health. one risk factor is dyslipidemia. evidence from molecular and animal research and epidemiologic investigations indicate that calcium intake may influence lipid metabolism.but intervention studies have produced conflicting results.objective of this study was to determine the effects of calcium supplementati...