AIMS/INTRODUCTION High fluctuations in blood glucose are associated with various complications. The correlation between glycated hemoglobin (HbA1c) level and fluctuations in blood glucose level has not been studied in Japanese patients with type 2 diabetes. In the present study, blood glucose profile stratified by HbA1c level was evaluated by continuous glucose monitoring (CGM) in Japanese type...

Background Larger platelets are more active and mean platelet volume (MPV) is an indicator of platelet activation and an independent risk factor of cardiovascular diseases. While MPV is reported to be higher in diabetic patients, the relationship between MPV and glycemic parameters in general population remains inconclusive. Methods In this cross-sectional study, we studied relationship betwe...

BACKGROUND AND PURPOSE Glycated hemoglobin (HbA1c) reflects the cumulative glucose exposure of erythrocytes over a preceding time frame proportional to erythrocyte survival. HbA1c is thus an areal function of the glucose-time curve, an educationally useful concept to aid teaching and clinical judgment. METHODS An ordinary differential equation is formulated as a parsimonious model of HbA1c. T...

Amaç: Diabetes mellitus (DM) tanılı gebelerde glikolize hemoglobin A1C (HbA1c) düzeyleri ile gebelikte meydana gelebilecek olan komplikasyonlar arasında ilişki olup olmadığını saptamak.
 Gereç ve Yöntemler: Çalışmamız retrospektif vaka-kontrol çalışmasıdır. Ocak 2013 Aralık 2017 tarihleri Aydın Adnan Menderes Üniversitesi hastanesinde yapılmıştır. 321 hasta üzerinde Hastalarda HbA1C düzeyi...

OBJECTIVE To examine the association of hemoglobin (Hb) A1c variability with microvascular complications in the large cohort of subjects with type 2 diabetes from the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study. RESEARCH DESIGN AND METHODS Serial (3-5) HbA1c values collected in a 2-year period before enrollment were available from 8,260 subjects from 9 cent...

An electrochemical immuno-biosensor for detecting glycosylated haemoglobin (HbA1c) is reported based on glassy carbon (GC) electrodes with a mixed layer of an oligo(phenylethynylene) molecular wire (MW) and an oligo(ethylene glycol) (OEG). The mixed layer is formed from in situ-generated aryl diazonium cations. To the distal end of the MW, a redox probe 1,1'-di(aminomethyl)ferrocene (FDMA) was ...

BACKGROUND The role of glycated hemoglobin (HbA1c) in the prediction of ischemic stroke in non-diabetic subjects is not clear. We performed a study to analyze the role of HbA1c in the risk prediction of ischemic stroke in non-diabetic Korean males adult. METHODS A total of 307 non-diabetic male patients with ischemic stroke were enrolled, and 253 age-matched control subjects without a history...