The complexities of cellular regulations seem to never end. RNA, in particular, appears to exert ever-new regulatory functions in an astonishing variety of ways. miRNAs are especially wondrous, in that they can modulate hundreds of targets at once. Dissecting the cellular effects of myriad such multiplex regulations will probably keep biologists busy for many years to come. in this issue of Cel...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Trzepizur M, Toporowska-Kowalska E. Application of faecal calprotectin as marker gastrointestinal tract disorders. Pediatria Polska - Polish Journal of Paediatrics. 2021;96(3):198-206. doi:10.5114/polp.2021.109306. APA Trzepizur, M., & Toporowska-Kowalska, (2021). Paediatrics, 96(3), 198-206. https://doi.org/10.5...

Ninety-one strains of Pseudomonas pseudomallei were tested in the API 20E system and in equivalent conventional tests. Except for utilisation of citrate there was good correlation between API and conventional tests. Seven-digit profiles were constructed from each strain after 48 hours' incubation, and numerical codes 2 006 727, 2 206 706, 2 206 707, and 2 206 727 accounted for 77% of strains te...

In the course of our screening program to discover antimalarial antibiotics, which are active against drug resistant Plasmodium falciparum in vitro and rodents infected with P. berghei in vivo, from the culture broth of microorganisms, we found a selective and potent active substance produced by an actinomycete strain K99-0413. It was identified as a known polyether antibiotic, X-206. We also c...

Many microRNAs (miRNAs), posttranscriptional regulators of numerous cellular processes and developmental events, are downregulated in tumors. However, their role in tumorigenesis remains largely unknown. In this work, we examined the role of the muscle-specific miRNAs miR-1 and miR-206 in human rhabdomyosarcoma (RMS), a soft tissue sarcoma thought to arise from skeletal muscle progenitors. We h...