Background and Aims: Plants as medicines have always played a vital role in human life. Tumor necrosis factor alpha (TNF)-α is one of the macrophage-derived inflammatory cytokine with pleotropic effects in the inflammation process. Some studies have been demonstrated that some of the Echinops species have anti-inflammatory activity. In fact, Echinops lasilepis is introduced as one of the ...

introduction: effects of immediate tnf-α exposure on phenotype and function of dendritic cells (dcs) derived from cord blood mono nuclear cells materials and methods: umbilical cord blood mncs were isolated from healthy mothers and were divided into tnf(+( and tnf (-) groups. both were cultured using scf, flt3l, gm-csf and il-4. but, three ng/ml of tnf-α was first added in the culture of tnf(+(...

Objective: This study aims to investigate the clinical importance of serum interleukin (IL) 6, IL-10, tumor necrosis factor alpha (TNF-alpha), neopterin, and plasma soluble urokinase plasminogen activator receptor (suPAR) levels in patients with pandemic H1N1 influenza infection and outpatients diagnosed with upper respiratory infections. Materials and Methods: Twenty-six inpatients with H1N1 i...

To investigate the effect of intracerebral adipose neural stem cell transplantation in inflammatory process after brain HI. The study used 16male Wistar rats aged 2 months which were randomly divided into following group: Ischemia-Reperfusion group (IR, n=8) and ANSC-treated (IR+ANSC, n=8). IR was performed by right common carotid artery occlusion for hours, hypoxia procedure 1 hour reperfusion...

Behçet's disease (BD) is a complex, multisystemic inflammatory disorder of unclear etiology. Single nucleotide polymorphisms in tumor necrosis factor (TNF) and interleukin (IL)-10 genes have been implicated in susceptibility to BD with inconsistent results in several ethnic populations. The aim of this case-control study was to evaluate the association of TNF-α (-308G/A), TNF-β (+252A/G), and I...