OBJECTIVE To investigate the effect of cyclosporin A (CyA) therapy on circulating concentrations of interleukin-6 (IL-6) and soluble interleukin-2 receptor (sIL-2R) in patients with rheumatoid arthritis (RA). METHODS Twenty four RA patients with active disease were studied. Plasma was collected before and after 16 weeks of CyA treatment. IL-6 was measured by B9 bioassay and sIL-2R by enzyme l...

An intriguing set of points of a generalised quadrangle was introduced in [2] as a unification of the pre-existing notions of tight set and m-ovoid. It was shown in [2] that every intriguing set of points in a finite generalised quadrangle is a tight set or an m-ovoid (for some m). Moreover, it was shown that an m-ovoid and an i-tight set of a common generalised quadrangle intersect in mi point...

The gene encoding a (2R,3R)-2,3-butanediol dehydrogenase from Rhodococcus erythropolis WZ010 (ReBDH) was over-expressed in Escherichia coli and the resulting recombinant ReBDH was successfully purified by Ni-affinity chromatography. The purified ReBDH in the native form was found to exist as a monomer with a calculated subunit size of 37180, belonging to the family of the zinc-containing alcoho...

Four rapid, simple, reproducible and sensitive methods (A-D) for assaying domperidone (I) and metoclopramide (II) in a bulk sample and in dosage forms were investigated. The first and second methods, A and B, are based on the oxidation of I and/or II by Fe3+ in the presence of o-phenanthroline (o-phen) or bipyridyl (bipy). The formation of tris-complex upon reactions with Fe3+-o-phen and/or Fe3...

We introduce the multiset partition algebra, ${\rm M\!P}_{r,k}(x)$, that has bases elements indexed by partitions, where $x$ is an indeterminate and $r$ $k$ are non-negative integers. This algebra can be realized as a diagram generalizes algebra. When integer greater or equal to $2r$, we show M\!P}_{r,k}(x)$ isomorphic centralizer of symmetric group, $S_n$, acting on polynomial ring variables $...

We consider the optimal rate of approximation by single hidden feed-forward neural networks on the unit sphere. It is proved that there exists a neural network with n neurons, and an analytic, strictly increasing, sigmoidal activation function such that the deviation of a Sobolev class W²(2r)(S(d)) from the class of neural networks Φ(n)(ϕ), behaves asymptotically as n(-2r/d-1). Namely, we prove...

Graphs are attached to 2r where 2r is the ring with 2 r elements using an analogue of Euclidean distance. M.R. DeDeo (2003) showed that these graphs are non-Ramanujan for r 4. In this paper, we will show that finite Euclidean graphs attached to 2r are non Ramanujan for r 2 except for r = 2 and d = 2, 3. Together with the results in Medrano et al. (1998), this implies that finite Euclidean graph...