Administration of ethanol (95%) extract (45 mg/kg body wt/day for 28 days) of garlic (A. sativum) to alloxan induced diabetic (ALX-D) mice significantly lowered the serum glucose levels, nociceptive response in tail-flick, hotplate, allodynia, formalin test and relative thickness, weight of hind paw in formalin induced Paw oedema test, over 28 days, thus, showing the reversal trend in hyperglyc...

The aim of this review was to evaluate the effect of different preparations of garlic with different methodologies on prevention and control of cardiovascular disorders. Almost 30 articles and abstracts from 1990-2003 were searched through Medline. Most of the studies between 1990-1993 showed the significant reduction of TC by garlic powder but a recent controlled study in 2000 found that consu...

in this study, we investigated the effect of savory (satureja hortensis) essential oil, garlic(allium sativum) powder, and garlic aqueous extract on fungal load of poultry feed. tothis end, savory essential oil and garlic aqueous extract each amounting 62.5, 125, and250 μl/ml and mg/ml, respectively, per kilogram of feed and garlic powder amounting2.5, 5, and 10 g/kg of feed were used. one and ...

Emerging multidrug resistant bacterial infections are burning public health concerns worldwide. There is an urgent need to explore alternative antimicrobial agents for effective management of bacterial infections. Garlic (Allium sativum) has been traditionally used for the treatment of different diseases since ancient times. The present study aims to evaluate the antimicrobial activity of aqueo...

background and aims: influenza virus is the most important cause of annual morbidities and mortalities worldwide with numerous antigenic drifts and shifts. inaccessibility to effective drugs and vaccines has made world health authorities to be interested in traditional medicine in order to prevent spread of the infectious agent. garlic is one of the most famous of all plants in human history. i...

Recent studies have cast doubt on the proposed lipid-lowering and blood pressure-lowering effects of garlic. We tested the effect of dried garlic (Allium sativum) powder on blood lipids, blood pressure and arterial stiffness in a 12-week randomised, double-blind, placebo-controlled trial. Seventy-five healthy, normo-lipidaemic volunteers (men and women aged 40-60 years) were assigned to dried g...

The hypotensive effect of garlic has been well-documented in human subjects and animals. Since endothelial activity regulates vascular reactivity in physiological and pathophysiological conditions, the aim of the present study was to investigate the effect of garlic on endothelium-dependent and independent relaxation of rat aorta for elucidation of mechanism of the garlic anti-hypertensive effe...

introduction: the most important virulence factor of brucella is related to its capability of intraphagocytic survival. brucella with this ability,causes persistant infection in host. garlic extract, because of has organosulfur compounds such as allicin, has antimicrobial activity. the aim of this study was to investigate the effect of garlic choloroformic extract on intramacrophage brucella sp...