The development of green, sustainable, and atom‐economical procedure for the construction amides via C‐N bond formation is a high priority in synthetic organic community. In this research article, we demonstrate simple an efficient catalytic protocol N‐alkylation benzamides/sulfonamides using aromatic primary alcohols as coupling partners through borrowing hydrogen (BH) strategy by employing ne...

Benzyl Alcohol Dehydrogenase (BADH) is an important enzyme for hydrocarbon degradation, which can oxidize benzyl alcohols to aldehydes, while being capable of catalyzing a reversible reaction by reducing benzaldehyde. BADH is a member of medium chain alcohol dehydrogenases, in which zinc and NAD are essential for enzyme activity. This paper describes the expression, purification, and characteri...

background and aims: alcohol abuse is an important concern of many societies. hippocampal neurogenesis regulates abusing drugs in a positive manner. the aim of this study was to identify factors that regulate neurogenesis in isolation period that increase preference for alcohol and salt. materials and methods: in this study sixteen rats were randomly divided into two groups: pair (social) and i...

Key words potassium fluoride - amino acid deprotection peptides fluorenylmethyl carbamates amides one-pot synthesis

A relatively simple and rapid procedure for the measurement of free ammonium and the amides in plant extracts is described. The method was developed by combining a cation-exchange method for blood ammonia with a differential acid-hydrolysis procedure for asparagine and glutamine amide-nitrogen. The recovery of standard samples (100-400 mug of ammonium- or amide-nitrogen) of free ammonium, aspar...

Novel rel-(5R,6S,7S)-2-oxo-5-phenyl-7-aryl(hetaryl)-3,7-dihydro-2H-thiopyrano [2,3-d]thiazole-6-carboxylic acid amides were synthesized in a hetero-Diels-Alder reaction with a series of cinnamic acid amides. The synthesized compounds were tested for their anticancer activity in vitro in the standard National Cancer Institute 60 cancer cell line assay. Promising compounds 3e, 3g, and 3h with mod...

[reaction: see text] An efficient one-step amination of cyclic amides and ureas has been developed. Treatment of cyclic amides and cyclic ureas with BOP in the presence of DBU in various solvents led to the formation of cyclic amidines and cyclic guanidines in good to excellent yields. Concise syntheses of biologically intriguing kinetin and potent kinase inhibitor olomoucin were thus achieved ...

Ferric hydrogensulfate catalyzed the synthesis of 5-substituted 1H-tetrazoles via [2 + 3] cycloaddition of nitriles and sodium azide. This method has the advantages of high yields, simple methodology, and easy workup. The catalyst can be recovered by simple filtration and reused delivering good yields. Also, ferric hydrogensulfate catalyzed the hydrolysis of nitriles to primary amides under aqu...

Derivatives of the fully twisted bicyclic amide 7-hypoquinuclidone are synthesized using a Schmidt-Aubé reaction. Their structures were unambiguously confirmed by X-ray diffraction analysis and extensive spectroscopic characterization. Furthermore, the stability and chemical reactivity of these anti-Bredt amides are investigated. 7-Hypoquinuclidonium tetrafluoroborate is shown to decompose to a...

When the high power ultrasound irradiates the liquid, small liquid droplets are generated from the liquid surface. This phenomenon is called as ultrasonic atomization [1]. Recently, it has been reported that ethanol is concentrated from the aqueous solution by ultrasonic atomization [2-4]. Since ultrasonic atomization scarcely accompanies the phase change, this is a great advantage comparing wi...