background: reactive oxygen species (ros)-induced lipidperoxidation can lead to dysfunction of sperm and thereby, infertility may be occurred. so, always there is a balance between amount of ros and anti-oxidant molecules in semen. anti-oxidant enzymes of sperm; superoxide dismutase (sod), glutathione peroxidase (gpx), catalse and zinc and selenium can protect it from destructive effects of ros...

Oxidative mechanisms of injury are important in many neurological disorders, including hypoxic-ischemic brain damage. Cerebral palsy after preterm birth is hypothesized to be caused by hypoxic-ischemic injury of developing oligodendrocytes (OLs). Here we examined the developmental sensitivity of OLs to exogenous hydrogen peroxide (H2O2) with stage-specific rat oligodendrocyte cultures. We found...

background & aim:extracts of roselle calyx,   possess compounds which could be considered as a great source of natural antioxidants.   in this project, antioxidant activities, phenolic compounds content and their   correlation analysis on calices of roselle (hibiscus sabdariffa) was investigated.  experimental: total polyphenolic compound, flavonoids and anthocyanins were determined spectrophot...

selenium is an essential element for humans, therefore, adding it to plants is convenient for biofortification. thus, the aim of this work was to analyze experimentally the ability of sodium selenite to increase the concentration of se and modify the antioxidant activity in tomato plants. we used plants of the toro hybrid variety and applied three treatments: 0, 2 and 5 mg l-1 of selenium as so...

OBJECTIVE While evidence for oxidative injury is frequently detected in brains of humans affected by Parkinson's disease (PD) and in relevant animal models, there is uncertainty regarding its cause. We tested the potential role of catalase in the oxidative injury that characterizes PD. METHODS Utilizing brains of A53T α-Syn and ntg mice, and cultured cells, we analyzed catalase activity and e...

Isoniazid, is the only antituberculous drug for which the relation between lack of virulence and acquisition of resistance was associated. INH-resistant mutants were shown to contain defective katG gene. Classical studies showed that INH-resistant south Indian isolates have lower virulence in guinea pigs and higher susceptibility to H2O2. It is of interest to assess the virulence in south India...

Peroxidatic activity of catalase (E .C .1 .11 .1 .6) was discovered by Keilin and Hartree (1), and it has been firmly established that, catalase oxidizes various substrates such as ethanol, methanol, nitrite, and formate (2-4) . Crystalline beef liver catalase, used as an enzyme tracer (5), and the peroxisomal catalase (6, 7) have been visualized cytochemically by a modification of the 3,3'diam...