Substitute valuations (in some contexts called gross substitute valuations) are prominent in combinatorial auction theory. An algorithm is given in this paper for generating a substitute valuation through Monte Carlo simulation. In addition, the geometry of the set of all substitute valuations for a fixed number of goods K is investigated. The set consists of a union of polyhedrons, and the max...

Substitute valuations (in some contexts called gross substitute valuations) are prominent in combinatorial auction theory. An algorithm is given in this paper for generating a substitute valuation through Monte Carlo simulation. In addition, the geometry of the set of all substitute valuations for a fixed number of goods K is investigated. The set consists of a union of polyhedrons, and the max...

Objectives After reading this article, the reader will be able to:  Briefly discuss the significant milestones in the search for a substitute for human blood.  List several factors driving the search for a blood substitute.  List the characteristics of an ideal blood substitute.  Name and explain the four phases of clinical trials required before a drug can be approved by the Food and Drug ...

BACKGROUND A tube feeding decision aid designed at the Ottawa Health Research Institute was specifically created for substitute decision-makers who must decide whether to allow placement of a percutaneous endoscopic gastrostomy (PEG) tube in a cognitively impaired older person. We developed a Japanese version and found that the decision aid promoted the decision-making process of substitute dec...

BACKGROUND A phenylalanine-free amino acid based protein substitute is necessary to provide the major source of protein in phenylketonuria (PKU). Protein substitutes in PKU are usually given as drinks. These are unpalatable and compliance is often poor. Tablets containing a suitable mixture of phenylalanine-free amino acids (Aminogran Food Supplement, UCB) are now available. AIMS To compare t...

this study was conducted using one hundred and eighty (180) day-old broiler chicks, of anak strain to assess the levels of inclusion of indomie waste meal as a substitute for maize at 0, 25, 50, 75 and 100%. the birds were randomly assigned to dietary treatments using completely randomized design (crd). each treatment contained 3 replicates and each replicate had 6 birds. the study lasted for e...

Lack of cytocompatibility in bone substitutes impairs healing in surrounding bone. Adverse biological events around biomaterials may be associated with oxidative stress. We hypothesized that a clinically used inorganic bone substitute is cytotoxic to osteoblasts due to oxidative stress and that N-acetyl cysteine (NAC), an antioxidant amino acid derivative, would detoxify such material. Only 20%...

Introduction: Total Skin Electron Therapy (TSET) and Total Body Irradiation (TBI) are kinds of treatment which use electron and photon beams to treat special types of cancers. The aim of these techniques are to deliver uniform dose to the entire skin while minimizing delivered dose to organs at risk. To check the homogeneity of dose delivery in TBI and TSET, using a humanoid ph...

Benign primary bone tumors are commonly treated with intralesional curettage with or without the use of surgical adjuvants. The reconstructive approach to the resulting contained bone defects is controversial, and clinical practice is varied. Synthetic bone substitutes may provide early mechanical support while minimizing the risks of disease transmission, nonunion, infection, and donor-site mo...