Human group IIA phospholipase A(2) (hGIIA) is secreted from a number of cells during inflammation and is known to interact strongly with anionic membranes and to exhibit potent Gram-positive bactericidal activity. This protein contains 23 cationic residues, which are scattered over its entire surface, resulting in a high pI of 9.39. To understand the molecular basis for the selective binding of...

Aerial Dispersant application has changed platform in recent years with the introduction of worlds first jet platform; a Boeing 727 complete TERSUS dispersant delivery system. During development this platform, stringent measures were imposed to comply aviation standards, necessary obtain approval from authorities operate. Airframe icing occurs when ambient temperature is low enough allow water ...

Despite intense research in FLP chemistry, nothing is known about monomolecular anionic FLPs and/or complexes thereof. Herein, synthesis and reaction of the first anionic FLP complex is described using [(OC)5W{(Me3Si)2HCP(H)OLi(12-crown-4)}], Cy2BCl and subsequent deprotonation by KHMDS. The obtained anionic FLP complex reacts readily with CO2 in a concerted manner.

The aim of the present research is to convert bioinert surface of NiTi to bioactive and biocompatible surface. In order to develop a bioactive and corrosion resistant film on NiTi, electrophoretic deposition process was done and TiO2 particles were deposited on the NiTi surface. Suspensions including TiO2 particles were prepared using a mixture of acetone and n-butanol (0%, 30%, 60%, 80% and 10...

The distribution of anionic binding sites has been investigated in the isolated Golgi complex using cationic ferritin. The greatest density of anionic sites occurs on the tubular network and small vesicles, and this binding is accompanied by increased levels of galactosyltransferase activity. The density of anionic sites on the cisternae is less than on the tubules and shows anisotropic distrib...

The anionic [2,3] sigmatropic Wittig rearrangements of deprotonated 4-hetera-1-pentenes and the anionic [3,3] sigmatropic Cope rearrangements of 3-substituted-1,5-hexadienes were explored by using density functional theory calculations. While the deprotonated anionic 3-hydroxy-1,5 hexadiene (2a), 3-thiohydroxy-1,5-hexadiene (2c), and 3-formamidyl-1,5-hexadiene (2d) Cope substrates undergo conce...

Anionic states of nucleic acid bases are involved in DNA damage by low-energy electrons and in charge transfer through DNA. Previous gas phase studies of free, unsolvated nucleic acid base parent anions probed only dipole-bound states, which are not present in condensed phase environments, but did not observe valence anionic states, which for purine bases are thought to be adiabatically unbound...