نتایج جستجو برای: antibiotic use
تعداد نتایج: 1812809 فیلتر نتایج به سال:
BACKGROUND There are no reliable data on antibiotic use in non-European Union (EU) southern and eastern European countries and newly independent states. We aimed to collect valid, representative, comparable data on systemic antimicrobial use in these non-EU countries of the WHO European region. METHODS Validated 2011 total national wholesale antibiotic-use data of six southern and eastern Eur...
BACKGROUND Inappropriate antibiotic use promotes resistance. Antibiotics are generally not indicated for upper respiratory infections (URIs). Our objectives were to describe patterns of URI treatment and to identify patient and provider factors associated with antibiotic use for URIs. METHODS This study was a cross-sectional analysis of medical and pharmacy claims data from the Pennsylvania M...
Bacterial resistance to antibiotics is a growing clinical problem and public health threat. Antibiotic use is a known risk factor for the emergence of antibiotic resistance, but demonstrating the causal link between antibiotic use and resistance is challenging. This review describes different study designs for assessing the association between antibiotic use and resistance and discusses strengt...
M. T. Baysari1,2; K. Oliver2; B. Egan2; L. Li3; K. Richardson4; I. Sandaradura5; J. I. Westbrook3; R. O. Day2,6 1Australian Institute of Health Innovation, UNSW Medicine, University of New South Wales, Sydney, Australia; 2Department of Clinical Pharmacology & Toxicology, St Vincent’s Hospital, Sydney, Australia; 3Centre for Health Systems & Safety Research, Australian Institute of Health Innova...
OBJECTIVES Antibiotic use in childhood has been hypothesized to increase the risk of intussusception. Antibiotics have well-known effects on gut motility and microflora-possible mechanisms for the hypothesized association. We evaluated the risk of intussusception according to antibiotic use. METHODS We conducted a nationwide cohort study of all Danish singleton children born between 1995 and ...
To the Editor: The article by Harris et al., published in the August 2007 issue of Emerging Infectious Diseases, examined the risk factors for selecting extended-spectrum β-lactamase–producing Enterobacteriaceae in intensive-care patients and found that exposure to piperacillin/tazobactam and vancomycin were independent risk factors (1). Although antimicrobial drug use has been historically lin...
Establishing an effective antimicrobial therapeutic requires choosing the appropriate antibiotic and ensuring compliance with times and doses prescribed. Problems concerning early abandonment and unfinished prescriptions due to lack of information, as well as more resistant microorganisms, have been identified as the major factors responsible for therapeutic failure in bacterial infections. Thi...
BACKGROUND Residents in nursing homes have a higher risk of developing infections that require antibiotic treatment than elderly people living at home. Use of antibiotics may cause adverse effects and result in the development of antimicrobial resistance. MATERIAL AND METHOD Data on healthcare-associated infections and antibiotic use in 540 Norwegian nursing homes were retrieved from the Norw...
The changing pattern of organisms causing neonatal sepsis, from Streptococcus pyogenes in the 1930s to Staphylococcus aureus in the 1950s and more recently to Gram negative bacilli and the group B streptococcus,' has been reflected in the development of new antibiotics. In particular semi-synthetic penicillins and the so called third generation cephalosporins have been introduced, both with act...
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