Diabetes mellitus is an incapacitating and often serious disease with increasing prevalence in rural populations throughout the world. In the current study, the putative antihyperglycemic and antihypolipidemic effects of C. orchioides were evaluated in comparison with those of glyclazide, a standard drug for therapy of diabetes mellitus. Diabetes was induced experimentally in 12-hr fasted rats ...

Lagenaria siceraria (Mol.) Standley fruit (bottle gourd), a commonly used vegetable in India is described as cardiotonic and as a general tonic in Ayurveda. Keeping in view the presence of free radical scavenging activity in L. siceraria and involvement of free radicals in the development of various disorders, present studies were designed to evaluate the ethanolic extract of L. siceraria fruit...

H. italicum essential oil (EO) is one of the most popular ingredients utilized by cosmetic industry, and it also used as natural antioxidant a value-added ingredient in food products. The chemical composition EO cultivated Serbia was analyzed gas chromatography–mass spectrometry. quantitative structure–retention relationship to predict retention indices constituents acquired GC-MS data, applyin...

BACKGROUND Antihyperglycemic drugs have been linked to new-onset atrial fibrillation (NAF). However, the effect of the different classes of antihyperglycemic drugs on the development of NAF in elderly patients has not been well studied. In this study, we investigated the association between different classes of antihyperglycemic drugs and NAF in elderly patients. MATERIALS AND METHODS This wa...

OBJECTIVE The purpose of this study was to determine how patients' beliefs about antihyperglycemic and antihypertensive medications relate to medication underuse and health status. RESEARCH DESIGN AND METHODS In diabetic patients from an economically distressed region, we assessed perceived necessity and harmfulness for antihyperglycemic (n = 803) and antihypertensive (n = 573) medications, p...

INTRODUCTION Clerodendron infortunatum Linn. (Verbenaceae), commonly known as Bhant in Hindi, is a small shrub occurring throughout the plains of India, which is traditionally used for several medicinal purposes. The aim of the present study was to evaluate the preclinical antihyperglycemic activity of the methanol extract of the leaves of C. infortunatum (MECI) in Wistar rats. METHODS Hyperg...

Antihyperglycemic potential of hyperin at 25 and 50 mg/kg doses for 30 days to streptozotocin induced diabetic rats has been reported. In oral glucose tolerance test, hyperin treated rats showed a significant reduction in blood glucose level after 120 min. It was found that hyperin exhibited dose dependent and significant antihyperglycemic activity in streptozotocin induced diabetic rats which ...