OBJECTIVE To determine factors predictive of the score on the visual analogue scale (VAS) of the EQ-5D questionnaire. METHODS The responses of 1159 residents of a socially and ethnically diverse suburb of Cape Town, South Africa, to the EQ-5D questionnaire were analysed using forward stepwise multiple regression. The variables entered included ethnic group, religious affiliation (Christian or...

BACKGROUND The validity of Health-Related Quality of Life (HRQOL) recalled by ICU admitted patients have not been published. The aim of this study was to compare the baseline HRQOL measured before surgery and ICU admission with that recalled at 3 and 6 months in a population of patients with planned ICU admission after surgery. METHODS This prospective study was performed in three Italian cen...

INTRODUCTION Health utilities of tuberculosis (TB) patients may be diminished by side effects from medication, prolonged treatment duration, physical effects of the disease itself, and social stigma attached to the disease. METHODS We collected health utility data from Thai patients who were on TB treatment or had been successfully treated for TB for the purpose of economic modeling. Structur...

OBJECTIVES This study aimed to measure the level and determinants of health-related quality of life (HRQoL) in adults in Kermanshah, a city in the western region of Iran. METHODS Convenience sampling was employed to obtain a sample of 998 adults aged 18 years and older (646 males and 352 females) in the city of Kermanshah. A 2-part self-administered questionnaire was used to collect data over...

Ghana is an important cocoa producer and exporter this production of high economic importance. Increasing interest in the sustainable productions cocoa/chocolate necessitated need to assess environmental impacts associated with different chocolate variants (extra dark (EDC), (DC), milk (MC) flavoured (FMC) Ghana, including identification hotspots for improvement. The life cycle assessment tool ...

BAR domain proteins contribute to membrane deformation in diverse cellular processes. The inverted-BAR (I-BAR) protein IRSp53, for instance, is found on the inner leaflet of the tubular membrane of filopodia; however its role in the formation of these structures is incompletely understood. Here we develop an original assay in which proteins are encapsulated in giant unilamellar vesicles connect...

background β-thalassemia is a prevalent genetic disease in mediterranean countries. the most common treatments for this disease are blood transfusion plus iron chelation (btic) therapy and bone marrow transplantation (bmt). patients using these procedures experience different health-related quality of life (hrqol). the purpose of the present study was to measure hrqol in these patients using 2...

Objectives. To assess the validity, reliability, and responsiveness to change of a patient self-reported questionnaire combining the Widespread Pain Index and the Symptom Severity Score as well as construct outcome measures and comorbidities assessment in fibromyalgia patients. Methods. The PROMs-FM was conceptualized based on frameworks used by the WHO Quality of Life tool and the PROMIS. Init...

BACKGROUND CONTEXT Clinimetric properties of the EuroQol-5D (EQ-5D) in patients with nonspecific chronic low back pain (CLBP) are largely unknown. PURPOSE To study the criterion validity, responsiveness, and minimal clinically important change (MCIC) of EQ-5D in patients with CLBP. STUDY DESIGN Prospective study design carried out in a multispecialist Spine Center in The Netherlands. PATI...