There is currently lively debate as regards the diagnosis of bipolar disorder. Generally, there is consensus that bipolar I disorder, characterised by mania, is distinct as compared to unipolar major depression. This is demonstrated to some extent across the phenomenology, population characteristics, genetics and neurobiology of the two phenotypes. However, the diagnosis of bipolar II disorder ...

In this article, we review empirical research on the role of individuals' parenting and maltreatment histories as developmental antecedents for symptoms and diagnosable episodes of unipolar and bipolar spectrum disorders. Our review is focused on the following three overarching questions: (1) Do negative parenting and a history of maltreatment contribute risk to symptoms or diagnosable episodes...

OBJECTIVE Research of electroencephalograph (EEG) power spectrum and mean frequency has shown inconsistent results in patients with schizophrenic, schizoaffective and bipolar disorders during medication when compared to normal subjects thus; the characterization of these parameters is an important task. METHODS We applied quantitative EEG (qEEG) to investigate 38 control, 15 schizophrenic, 7 ...

BACKGROUND/AIMS Temperament and mood swings are promising indicators for the characterization of mood spectrum vulnerability. The aim of this study was to investigate the relationship between affective temperament and mood swings in bipolar disorder. We explored these clinical features retrospectively. METHODS Patients who met the criteria for bipolar I disorder were enrolled in the study. Ex...

OBJECTIVE To investigate the presence of temperament dysregulation in healthy relatives of bipolar probands (RBP), a population at high risk for developing mood disorders, by comparing them with clinically recovered bipolar patients (BP) and normal controls (NC). METHOD 52 RBP and 23 BP were originally recruited for a multicenter genetic study in bipolar disorders. NC (n=102) were also recrui...

The statistical expectation values of the temperature fluctuations of cosmic microwave background (CMB) are assumed to be preserved under rotations of the sky. We investigate the statistical isotropy of the CMB anisotropy maps recently measured by the Wilkinson Microwave Anisotropy Probe (WMAP) using bipolar spherical harmonic power spectrum proposed in Hajian & Souradeep 2003. The Bipolar Powe...

Since Kraepelin grouped affective disorders under the title of 'manic-depressive insanity', there has been controversy over whether the bipolar and unipolar entities within this are distinct affective disorders or whether they are merely two ends of an affective continuum. In order to bring some clarity and goal-posts to this argument, we define the criteria that must be fulfilled by diseases i...

conclusions the obtained results confirm some previous studies regardinga gender specific association of maoa gene with the bipolar disorder. results significant associations were observed regarding maoa-ca (p = 0.016) and maoa-vntr (p = 0.004) polymorphisms in the bipolar females. there was no association between maoa-rflp and bipolar disorder. patients and methods this study is a case-control...