BACKGROUND A large percentage of autogenous and homogenous grafts are resorbed and replaced by the recipient's own tissue. It is generally believed that autogenous grafts are superior to homogenous ones. The aim of our study was to compare the effectiveness of autografts and allografts in achieving the healing of a non-union of forearm bones. MATERIAL AND METHODS Between 1976 and 2005, 56 pat...

AIM Due to new medical knowledge and legal restrictions, it is increasingly difficult to run a traditional allogenic bone bank so that alternative bone substitutes and methods of processing are being sought worldwide. METHOD In a prospective clinical study, the biological efficacy of thermodisinfected and then cryopreserved allogenic bank bone was investigated in 19 acetabular revisions in 18...

A new entity called "implant periapical lesion" has recently been described. This lesion could be the result of, for example, bone overheating, implant overloading, presence of a preexisting infection or residual root fragments and foreign bodies in the bone, contamination of the implant, or implant placement in an infected maxillary sinus. This case report describes a titanium implant that was...

While effects of inhaled corticosteroids on serum markers of bone metabolism in normal and asthmatic subjects have been reported, there are little data on the direct effects of these corticosteroids on end-organs such as bone. The results presented here compare the effects of budesonide and its epimers (22S- and 22R-budesonide), fluticasone and dexamethasone on growth and differentiation of cul...

The accumulation of senescent cells is implicated in the pathology of several age-related diseases. While the clearance of senescent cells has been suggested as a therapeutic target for patients with osteoarthritis (OA), cellular senescence of bone-resident osteoblasts (OB) remains poorly explored. Since oxidative stress is a well-known inducer of cellular senescence, we here investigated the e...

This present investigation uses the Taguchi and response surface methodology (RSM) for modelling and optimization of the temperature produced during bone drilling. The drilling of bone is a common procedure in orthopaedic surgery to produce hole for screw insertion to fixate the fracture devices and implants. A major problem which is encountered during such a procedure is the increase in temper...

BACKGROUND Lumbar spondylolysis and isthmic spondylolisthesis are common conditions. However, double-level lumbar spondylolysis and spondylolisthesis are rare. We report 24 cases of it along with a review of literature and a briefly description of the clinical and radiological features and integrated management of patients with this condition. METHODS Of 1700 inpatients diagnosed with lumbar ...

Involvement of the iliac bone and a sacroiliac joint with malignant tumours is not uncommon; treatment is difficult due to the anatomy of the pelvis. Resection of the tumour mass must be extensive in order to achieve safe margins, but this may lead to instability and poor results. We present a new technique for reconstruction after resection of the iliac bone and sacroiliac joint including a sa...