background and objectives: the microbiological monitoring of the water used for haemodialysis is important especially for legionella and non-fermentative bacteria since patients with end stage renal disease (esrd) are suffering from deteriorated function of immune system. materials and methods: a total 50 water and dialysate samples were weekly collected over a period of 10 weeks from 5 sites. ...

A three-dimensional finite volume model of the blood-dialysate interface over the complete length of the dialyzer was developed. Different equations govern dialyzer flow and pressure distribution (Navier-Stokes) and radial transport (Darcy). Blood was modeled as a non-Newtonian fluid with a viscosity varying in radial and axial direction determined by the local hematocrit, the diameter of the c...

Microdialysis sampling of lipophilic molecules in human tissues is challenging because protein binding and adhesion to the membrane limit recovery. Hydroxypropyl-ß-cyclodextrin (HP-ß-CD) forms complexes with hydrophobic molecules thereby improving microdialysis recovery of lipophilic molecules in vitro and in rodents. We tested the approach in human subjects. First, we determined HP-ß-CD influe...

Evidence for the elaboration of a hormonal inhibitor of renal tubular reabsorption in response to expansion of extracellular fluid volume was obtained by examining the effects of plasma from rats and dogs undergoing saline diuresis on the rate of proximal tubular reabsorption measured both directly by micropuncture techniques and indirectly by clearance techniques. Intravenous infusion of plasm...

Radial inflow turbines are the preferred architecture for energy extraction from the organic Rankine cycle and the supercritical CO2 Brayton cycle at smaller scales. For such turbines it is possible for fluid to be delivered to the first stage by either a volute or plenum delivery system. For high pressure supercritical CO2 turbines, there are no fully documented fluid delivery systems in liter...

UNLABELLED Biomaterials composed of mammalian extracellular matrix (ECM) promote constructive tissue remodeling with minimal scar tissue formation in many anatomical sites. However, the optimal shape and form of ECM scaffold for each clinical application can vary markedly. ECM hydrogels have been shown to promote chemotaxis and differentiation of neuronal stem cells, but minimally invasive deli...