although spinal cord injury (sci) is one of the most common injuries after a road accident, there is no definite treatment for it. in this regard, nanotechnology has focused to retrieve damaged tissue function by designing of a biomaterial as a mimicking extracellular matrix to reduce inflammation, scar and lactate dehydrogenase, to fill the cyst and improve the graft integration, cell prolifer...

a 19-year-old man presented with a 5-year history of back pain radiating to the lower extremities and paresthesis of the toes during the last year. plain x-ray revealed a large cauliflower shaped exophytic mass at the level of t8, t9 and t10 vertebrae. computed tomography (ct) and magnetic resonance imaging (mri) showed an abnormal bony mass arising from the posterior arch of t9 with protrusion...

introduction: in 1989, the first successful umbilical cord blood transplantations (ucbts) was reported in a boy with fanconi's anemia, using umbilical cord (ucb) of his hla matched sister. cord blood transplantation is a good substitute for bone marrow or peripheral blood transplantation especially for children and small body size adults. methods: between 1998 and 2007 ,14 children(10 boys and ...

conclusions we found a relatively high value of tc and tg in our study. considering the relationship between high levels of lipids in the neonatal period and coronary artery disease in the adult population, we recommend future cohort studies for this statistical society. results of the 174 neonates, 97 were female. vaginal delivery was recorded in 79.8%. there were no significant differences re...

conclusions changes in neonatal leptin levels can reflect changes in the body fat tissue and neonatal birth weight and could be effective in predicting weight gain in newborns with mothers who have gestational diabetes and may reduce birth trauma or future complications. results serum leptin levels in the cord blood of mothers with gdm were significantly higher than in normal mothers. there was...

introduction spinal cord injury without radiological abnormality (sciwora) is a rare entity and usually involves the cervical spine. thoracic spine involvement is very rare due to the stability provided by the rib cage. the mechanisms of injury and pathophysiology are still debatable. case presentation we present a case of an adult male who had road traffic accident and presented with paraplegi...

Umbilical cord blood was previously considered a waste product. It is now used to treat variety of diseases. the that remains after childbirth in placenta and attached umbilical cord. Cord collected because stem cells found it can be hematopoietic genetic disorders. The study aimed see how effective video-assisted teaching on collection for cell therapy among antenatal women. A quasi-experiment...

Introduction: Spinal cord injury (SCI) is one of the most serious clinical diseases, which not only affects the patient's physical and mental status, but its effects will be spread to family and community. After severe spinal cord injury, astrocytes of the central nervous system (CNS) become reactive astrocytes, and play the main role of glial scar formation. The scar is a major obstacle to r...

Spinal cord injury induces the disruption of blood-spinal cord barrier and triggers a complex array of tissue responses, including endoplasmic reticulum (ER) stress and autophagy. However, the roles of ER stress and autophagy in blood-spinal cord barrier disruption have not been discussed in acute spinal cord trauma. In the present study, we respectively detected the roles of ER stress and auto...

bone marrow mesenchymal stem cells can differentiate into neurons and astrocytes after transplantation in the spinal cord injury of rats. although bone marrow mesenchymal stem cells are known to protect against spinal cord injury through anti-apoptotic effects, but generation of neural stem cells with large number and safety protocols unclear. in the present study, described the differentiation...