PURPOSE To evaluate whether the use of balanced salt solution (BSS) or an ophthalmic viscoelastic device (OVD) during hydrophilic acrylic intraocular lens (IOL) implantation variously impacts corneal endothelial cell characteristics in eyes undergoing uneventful phacoemulsifications. METHODS Prospective nonrandomized observational clinical trial. Patients were assigned either to the BSS plus(...

The corneal endothelium of 42 clear corneal transplants was studied with a specular microscope. The endothelial cell morphology was analysed by using a computerised image analysis system. A quantitative index was developed to study the degree of variation in cell size. By applying this objective index we observed that pleomorphism is independent of age, and considerable alteration occurs in cel...

Corneal stroma plays a pivotal role in normal visual function. Anatomically, it is located between the outer epithelium and the inner endothelium and is the thickest layer of the cornea. Keratocytes in the stroma produce a variety of cellular products, including growth factors/cytokines, extracellular matrix (ECM) components, and kinases. These products support normal corneal development and ho...

Dextran, with a minimal molecular weight of 40,000, can pass in and out of the corneal endothelium during storage in M-K medium. Results suggest that the degree of penetration of dextran depends on the length of storage and the condition of the endothelium.

Osmotically driven water flow across the corneal epithelium and endothelium has been measured as a function of temperature. For both membranes deviations from a single straight-line relationship are found in a logarithmic plot of hydraulic conductivity against 1/T. Both membranes show a high (14 to 16 kcal per mole) apparent activation energy at temperatures between 23 degrees C. and 5 degrees ...

To cite: Mansour AM. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016217023 DESCRIPTION A 77-year-old woman underwent pars plana vitrectomy for recurrent retinal detachment with silicone oil injection 10 years before presentation. Also the patient was placed on antiglaucoma medications. The patient had a history of recurrent corneal ulcerations in both eyes du...

The cornea is a central component of the camera eye of vertebrates and even slight corneal disturbances severely affect vision. The transcription factor PAX6 is required for normal eye development, namely the proper separation of the lens from the developing cornea and the formation of the iris and anterior chamber. Human PAX6 mutations are associated with severe ocular disorders such as anirid...

The eyes of 12 human embryos and. fetuses between the seventh week and the eighth month of pregnancy are examined. Immature cell junctions, connecting the loosely arranged mesenchymal cells which later form the comeal endothelium, are observed between the seventh and eighth week of gestation. Occluding junctions in the form of maculae occludentes appear in the eighth week when a solid cell laye...

To clarify the relationship between morphological changes in the corneal endothelium and ultraviolet (UV) radiation, specular microscopic examinations were performed on both eyes of 118 welders and 85 controls. The results showed: a decrease in the hexagonal cells in welders (20-29 years) in comparison with the controls (20-29) (p less than 0.05); an increase in the mean cell size of the endoth...