نتایج جستجو برای: cox 2

تعداد نتایج: 2552374  

بهروان, جواد, مصفا, فاطمه, نورمحمدی, زهرا, واحدی, سعیده, کلالی نیا, بی بی فاطمه,

Background and purpose: One of the major problems in chemotherapy is resistance to anti-cancer drugs. Recent studies have demonstrated a relationship between cyclooxygenase-2 (COX-2) expression and progression of multidrug resistance (MDR). One of the proteins involved in drug resistance is ABCG2 (ATP-binding cassette sub-family G member 2) that is often overexpressed in patients with cancer. T...

Journal: :iranian journal of pathology 2012
behrang kazeminegad abbas mirafsharieh freidoon solhjoo

background and objective: egfr and her-2 are two members of erbb/her family of type i transmembrane growth factor receptors. cox2 is an enzyme responsible for the conversion of arachidonic acid to prostaglandins, which has a major role in angiogenesis and can modelate tumor growth. the aim of this study was to determine the level of expression of egfr, her-2 and cox2 in colorectd cancer. mater...

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