It is generally known that severe plastic deformation processes with back pressure not only apply higher hydrostatic stress and more deformation compared to what a regular process can apply to a workpiece but also prevent surface defects in the workpiece during the process. Hydrostatic cyclic expansion extrusion (HCEE) was developed recently for processing long ultrafine-grained metals and allo...

The objective of this study was to determine the arterial responses to plasma lipid lowering alone or in combination with (1) estrogen replacement therapy or (2) hormone replacement therapy in surgically postmenopausal female monkeys with preexisting atherosclerosis. Eighty-eight female cynomolgus macaques were ovariectomized, fed an atherogenic diet for 24 months, and then assigned by randomiz...

BACKGROUND In case of orphan drugs applicability of the standard health technology assessment (HTA) process is limited due to scarcity of good clinical and health economic evidence. Financing these premium priced drugs is more controversial in the Central and Eastern European (CEE) region where the public funding resources are more restricted, and health economic justification should be an even...

Compromised computers have been a menace to both personal and business computing. In this paper, we tackle the problem of automated detection of break-ins of new unknown threats such as worms, spyware and adware on personal computers. We propose Break-IN DEtectoR (BINDER), a host-based break-in detection system. Our key observation is that many break-ins make extrusions, stealthy malicious outg...

While the conspicuous visual displays of anoles have been studied in great depth, the possibility that these lizards may also interact through chemical signalling has received hardly any consideration. In this study, we observed the behaviour of male brown anoles (Anolis sagrei) when introduced into an environment previously inhabited by female conspecifics, and compared it to when they were in...

Nonlinear dimensionality reduction aims at providing low-dimensional representions of high-dimensional data sets. Many new methods have been recently proposed, but the question of their assessment and comparison remains open. This paper reviews some of the existing quality measures that are based on distance ranking and K-ary neighborhoods. In this context, the comparison of the ranks in the hi...

The effect of electropulsing on the extrusion due to persistent slip bands (PSBs) and defects in PSBs was investigated. To extend service life improve structural safety, technology is needed repair fatigue damage such as cracks dislocations directly. It has been shown that damaged metallic materials delays crack initiation extends life, but detailed mechanism this not explained. When cyclic str...

The relation among microstructure and fatigue behavior of 2205/316L stainless steel dissimilar welded joints was investigated. Plates 6.35 mm in thickness with a single-V joint configuration were gas metal arc (GMAW) single pass by feeding at 6 m/min an ER2209 filler wire heat input 1.2 kJ/mm. Grain growth the high temperature-heat affected zone (HT-HAZ) occurred mostly mid-height plates, delim...