Cytotoxic activity of methanolic extract Artocarpus heterophyllus against A549, Hela and MCF-7 cell linesRajesh M.Patel, Sahil K. Patel

The aim of the study was to evaluate the in vivo and in vitro effects of antidepressant drugs on cytotoxic activity of rat spleen macrophages. In the in vivo experiment, rats were injected subcutaneously with two different doses (2 or 10 mg/kg) of desipramine, fluvoxamine and fluoxetine. The drugs were given once, for 2, 4 or 8 weeks. In the in vitro experiment, spleen macrophages were cultured...

Fourteen plant species collected in Iran and selected mainly on the basis of their antimicrobial and/or antifungal activities were evaluated for in vitro antiplasmodial and cytotoxic effects in a study designed to screen plant extracts with selective activity against Plasmodium falciparum. The methanol extracts of nine of the species tested exhibit activity against Plasmodium falciparum (MIC va...

Andrographolde is the major secondary metabolite from the plant Andrographis paniculata. It has been found to show cytotoxic activity. To improve the efficacy on cytotoxic activity, a series of new sulfonyl derivatives have been synthesized by structural modifications of the andrographolide at C-2 position. All the derivatives were tested for their cytotoxic activity against human small lung ca...

The current study evaluated the general toxicity, antioxidant, antimicrobial, and cytotoxic activity of extracts obtained from the rhizomes of Eremostachys azerbaijanica (Labiatae) as well as analyzed the potent extracts using GC-MS. Extracts of E. azerbaijanica in n-hexane, dichloromethane (DCM) and methanol (MeOH) were prepared using a Soxhlet apparatus. The antioxidant activity of the extrac...

Achillea (Asteraceae) comprises 115 species, which are mainly distributed in Europe, Asia, and North Africa and as an introduced plant in the New World. The genus Achillea, generally called Bumadaran in Persian, is well known for medicinal properties such as anthelmintic, anti-inflammatory and anti-microbial effects. Achillea has long been used in traditional medicine for treatment of neuralgia...

Achillea (Asteraceae) comprises 115 species, which are mainly distributed in Europe, Asia, and North Africa and as an introduced plant in the New World. The genus Achillea, generally called Bumadaran in Persian, is well known for medicinal properties such as anthelmintic, anti-inflammatory and anti-microbial effects. Achillea has long been used in traditional medicine for treatment of neuralgia...

Cytotoxic activity screening of ethyl acetate fungal extracts derived from the marine sponge Neopetrosia chaliniformis AR-01Muh. Ade Artasasta, Yanwirasti, Akmal Djamaan, Dian Handayani