the gene responsible for HD (HTT) was cloned, representing a major breakthrough in the field. HTT encodes a large protein that was named Huntingtin (Htt). The N-terminal portion of Htt contains a stretch of glutamines (the polyQ tract) and HD patients harbor pathogenic polyQ expansions (Andrew et al., 1993; Bates et al., 1998). Although the polyQ length can vary, all healthy individuals have fe...

Seismic recordings represent convolution of a source wavelet with physical properties of the Earth’s interior, thus different components of the seismic recordings (e.g. traveltime of seismic phases, amplitudes and seismic waveforms) can be used to image structures and compositions of the Earth (e.g. Iyer and Hirahara, 1993; Nolet, 2008; Romanowicz, 2003; Stein and Wysession, 2002). By using dif...

We present a detailed analysis of a hydrodynamic constitutive model recently applied to study the non-local viscosity of highly confined inhomogeneous fluids (Zhang et al 2004 J. Chem. Phys. 121 10778, Zhang et al 2005 J. Chem. Phys. 122 219901). This model makes the assumption that, for pore widths significantly greater than the width of the viscosity kernel, one can approximate the true inhom...

Zhang et al. (G. Zhang, D. Shoham, D. Gilichinsky, S. Davydov, J. D. Castello, and S. O. Rogers, J. Virol. 80:12229-12235, 2006) have claimed to have recovered influenza A virus RNA from Siberian lake ice, postulating that ice might represent an important abiotic reservoir for the persistence and reemergence of this medically important pathogen. A rigorous phylogenetic analysis of these influen...

1. Chen HT. A new pulmonary nematode of rats, Pulmonema cantonensis ng, nsp from Canton [in French]. Ann Parasitol. 1935;13:312–7. 2. Wang QP, Lai DH, Zhu XQ, Chen XG, Lun ZR. Human angiostrongyliasis. Lancet Infect Dis. 2008;8:621–30. doi:10.1016/ S1473-3099(08)70229-9 3. Zhang RL, Chen MX, Gao ST, Geng YJ, Huang DN, Liu JP, et al. Enzootic angiostrongyliasis in Shenzhen, China. Emerg Infect D...

Zhang et al. (2012) and Rozas et al. (2012) in this issue of Neuron find that cysteine string protein α, a protein involved in neurodegeneration, regulates vesicle endocytosis via interaction with dynamin 1, which may participate in regulating synaptic transmission and possibly in maintaining synapses.

32.1 Smoothed ANOVA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 586 32.1.1 Zhang et al.’s SANOVA proposal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 586 32.1.2 Maŕi-Dell’Olmo et al.’s SANOVA proposal . . . . . . . . . . . . . . . . . . . . . . . . . . . 588 32.2 Some Specific Application...

Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females, accounting for 23% of the total cancer cases and 14% of the cancer deaths (Jemal et al., 2011). Breast cancer is now also the leading cause of cancer death among females in economically developing countries, a shift from the previous decade during which the most common cause of cancer deat...

Background. Attention to the loyalty of fans to the long-term success of sports organizations has become increasingly important. On this note, it seems necessary to pay attention to the variables that predict and influence the loyalty of spectators. Objectives. The aim of this study was to determine the mediating role of satisfaction in the effect of team reputation and team quality on the loy...