in this article electrochemical determination of captopril at the surface of the platinum coated nanoporous gold film (ptnpgf) electrode is reported using the cyclic voltammetry and amperometry. for the preparation of ptnpgf, the surface of npgf electrode was covered with cu layer using underpotential electrochemical deposition (upd).afterward, the copper layer is replaced with platinum ions vi...

in this work we sought to determine whether vesicles (liposomes/niosomes) were able to enhance finasteride concentration in the dermis layer, including the pilosebaceous units (psu). such enhancement could be beneficial in the treatment of some androgen-related skin disorders. hamster flank skin was used to study  3hfinasteride permeation via vesicles and a hydroalcoholic solution (ha). the dru...

The presence of pseudoexfoliation material on the surface of an intraocular lens (IOL) is a rare finding. We report a series of seven cases with different patterns of pseudoexfoliation material deposition on the posterior chamber IOLs, recognized 2-20 years after cataract surgery. Six patients had an IOL implanted in the capsular bag and one in the ciliary sulcus. Two patients had undergone pos...

Deposition of the major histone H3 (H3.1) is coupled to DNA synthesis during DNA replication and possibly DNA repair, whereas histone variant H3.3 serves as the replacement variant for the DNA-synthesis-independent deposition pathway. To address how histones H3.1 and H3.3 are deposited into chromatin through distinct pathways, we have purified deposition machineries for these histones. The H3.1...

A combined wet and dry cleaning process for GaN(0001) has been investigated with XPS and DFT-MD modeling to determine the molecular-level mechanisms for cleaning and the subsequent nucleation of gate oxide atomic layer deposition (ALD). In situ XPS studies show that for the wet sulfur treatment on GaN(0001), sulfur desorbs at room temperature in vacuum prior to gate oxide deposition. Angle reso...

The dynamic roughening of amorphous silicon nitride growth front prepared by a plasma-enhanced chemical vapor deposition is presented. Morphology of the films grown at different substrate temperatures ~from 50 to 350 °C! for various lengths of deposition time was measured ex situ using atomic force microscopy. The dynamic scaling exponents are measured as a;0.77, b;0.40, and 1/z;0.28, and do no...

The study of ventricular hypertrophy has recently been a fruitful research area. From studies principally in neonatal rat ventricular myocytes in primary culture but now increasingly in transgenic mice, the molecular mechanisms involved in this important pathophysiological adaptation are becoming clearer.1 In culture, cardiomyocyte hypertrophy is characterized by numerous transcriptional and mo...

Molecular mechanisms of electrophoretic deposition (EPD) of poly(3-decylthiophene) (P3DT) molecules onto vertically aligned cadmium selenide arrays have been studied using large-scale, nonequilibrium molecular dynamics (MD), in the absence and presence of static external electric fields. The field application and larger polymer charges accelerated EPD. Placement of multiple polymers at the same...

The fundamental mechanisms of diamond growth occur on the atomic scale. However, the geometry of the deposition reactor and the other operating parameters directly affect the chemical composition of the gas and the temperature at the growth surface. The properties are in turn controlled by both atomicand microstructural-scale features. By developing diamond growth models at each length scale an...

The deposition of a basement membrane by primitive endoderm cells is necessary for polarization of the epiblast and formation of the proamniotic cavity in periimplantation mammalian embryos. The synthesis of this basement membrane is in turn dependent upon laminin expression. Here we have used embryoid bodies derived from mouse embryonic stem cells to investigate the molecular mechanisms contro...