PURPOSE Recently, intravitreal injection of corticosteroids has been in wide use as a treatment for diabetic macular edema, and the outcomes have been favorable. However, the exact mechanism remains unclear. The hypothesis for the current study was that intravitreal corticosteroids may improve diabetic retinal edema by amelioration of blood-retinal barrier (BRB) breakdown, by inhibiting leukocy...

Diabetic macular edema (DME) is defined as excess fluid accumulation within the retina in area, and when it centered on fovea most common cause of decreased visual acuity patients with diabetic retinopathy. The development closely related to duration diabetes, poor glycemic control, type 2 diabetes insulin therapy. first-line therapy has been intravitreal injection anti-vascular endothelial gro...

Giant cell granuloma is rare in the head and neck region and most commonly affects the maxilla and mandible. Giant cell granulomas are benign but occasionally aggressive lesions that are traditionally treated with surgery. Because it is a benign process, less radical and non-surgical treatment alternatives are required. Corticosteroid injection is a viable alternative in the treatment of centra...

PURPOSE We designed a prospective, randomized study to evaluate the effects of iontophoresis delivery of dexamethasone versus corticosteroid injection therapy on patient outcomes. METHODS We randomized 82 patients to 10 mg dexamethasone via iontophoresis using a self-contained patch with a 24-hour battery; 10 mg dexamethasone injection; or 10 mg triamcinolone injection. All patients received ...

Impaired baroreflex sensitivity in diabetes is well described and has been attributed to autonomic diabetic neuropathy. In the present study conducted on acute (10-20 days) streptozotocin (STZ)-induced diabetic rats we examined: 1) cardiac baroreflex sensitivity, assessed by the slope of the linear regression between phenylephrine- or sodium nitroprusside-induced changes in arterial pressure an...

Background: EMLA cream is a eutectic mixture of Lidocaine and Prilocaine used to induce local anesthesia for dermatological procedures. Objective: This study was designed to evaluate the efficacy of EMLA cream in reducing the pain of intralesional injection of steroid in patients with alopecia areata. Patients and Methods: This study was carried out on 27 alopecia areata patients. The injection...

Diabetic rats in long-term display an augmented nociceptive response to thermal stimuli. Furthermore, hyperalgesia is one of the major symptoms of diabetic neuropathy in some patients. Considering the antidiabetic potential of medicinal plants chard, pepper, and tarragon, this study was undertaken to evaluate the possible analgesic effect of chard-, pepper-, and/or tarragon-mixed food intake in...

cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. in this study, the effect of chronic administration of sesame (sesamum indicum l) seed feeding was studied on aortic reactivity of streptozotocin (stz)-diabetic rats. male diabetic rats received sesame seed-mixed food at weight ratios of 3% and 6% for 7 weeks, one week after diabetes in...