Diabetic nephropathy in type 2 diabetic patients is a frequent complication associated with increased morbidity and mortality. Various growth factors and cytokines have been implicated in the pathogenesis of diabetic kidney disease, including vascular endothelial growth factor (VEGF). To explore a role for VEGF in renal changes in type 2 diabetes, we examined the renal effects of a neutralizing...

people with diabetes mellitus have a high risk of anxiety and stress and anxiety is higher in patients with diabetes who have long-term complication. the aim of this study was to assess and compare the prevalence of anxiety and stress in diabetic patients with and without complication attending to diabetes clinic of ebn sina hospital of delfan, iran. in this descriptive-comparative study, 239 t...

purpose : chlamydia pneumonia is a known endothelial pathogen in several vascular diseases including atherosclerosis, age-related macular degeneration and non-arteritic anterior ischemic optic neuropathy. diabetic retinopathy is a retinal vascular disease that may similarly be affected. we serologically investigated the presence of c. pneumonia infection in patients with proliferative diabetic ...

BACKGROUND: Diabetic coma is a common diabetes mellitus complication. The study of carbohydrate status usually conducted with non-violent death; however, the death patients can occur various types violent death. This aimed to describe and analyze rare expert cases circumstances in mellitus.
 CASE PRESENTATION: publication presents two mellitus, which cause was precomatous state, beginning ...

PURPOSE To study the effects of genistein, a tyrosine kinase inhibitor, on retinal vascular permeability in an experimental diabetic rat model. METHODS Seventy-two rats were equally divided into four groups: (1) nondiabetic control group, (2) diabetic control group, (3) diabetic rats receiving 150 mg genistein/kg food, and (4) diabetic rats receiving 300 mg genistein/kg food. Diabetes was ind...

Angiotensin-converting enzyme (ACE) inhibitors appear to correct many of the abnormalities associated with the vascular dysfunction found in diabetic patients. In this respect, quinapril is a unique ACE inhibitor with multiple protective effects. The present study was carried out to investigate the effect of intraperitoneal administration of quinapril on the aortic reactivity of streptozotocin ...

We analysed the complication rate in 140 below-knee amputations in relation to surgical technique and the presence of diabetes. In all cases, the skin perfusion pressure was measured below the knee before operation to provide an objective evaluation of the microcirculation. In diabetic patients we found a significantly higher complication rate after using a long posterior flap than after equal ...

Diabetes mellitus is one of the risk factors in the development of vascular complications. Decreased nitric oxide (NO) production and increased lipid peroxidation in diabetes mellitus are the dominant exaggerating factors. Mormodica charantia (MC) was proven to be useful in improving diabetes mellitus and its complications. In the present study, a total of 40 male Sprague-Dawley rats were used....