Proper vascular access function is required for efficient dialysis. With an unchanged incidence of patients undergoing renal replacement therapy and an increasing life expectancy, an increase in the insufficiency of dialysis accesses has accordingly been seen [1]. By maintaining long-term function, the use of dialysis catheters associated with a higher mortality rate can be avoided [2]. The mos...

Proper vascular access function is required for efficient dialysis. With an unchanged incidence of patients undergoing renal replacement therapy and an increasing life expectancy, an increase in the insufficiency of dialysis accesses has accordingly been seen [1]. By maintaining long-term function, the use of dialysis catheters associated with a higher mortality rate can be avoided [2]. The mos...

Proper vascular access function is required for efficient dialysis. With an unchanged incidence of patients undergoing renal replacement therapy and an increasing life expectancy, an increase in the insufficiency of dialysis accesses has accordingly been seen [1]. By maintaining long-term function, the use of dialysis catheters associated with a higher mortality rate can be avoided [2]. The mos...

INTRODUCTION Continuous exposition of the peritoneal membrane to conventional dialysis solutions is an important risk factor for inducing structural and functional alterations. OBJECTIVE To compare in vitro mouse fibroblast NIH-3T3 cell viability after exposition to a neutral pH dialysis solution in comparison to cells exposed to a standard solution. METHODS Experimental study to compare th...

BACKGROUND The purpose of this study was to evaluate the feasibility of utilizing an in-vitro, closed loop hemodialysis system as a method to assess drug clearance. Secondarily, this study tested the influence of variables (blood flow rate, dialysate flow rate, and type of filter) in the hemodialysis procedure on the clearance of vancomycin and gentamicin. METHODS An in-vitro, closed loop hem...

H emodialysis vascular access is the lifeline for more than 400,000 patients on hemodialysis in the United States. Unfortunately, due to the high incidence of dialysis vascular access dysfunction, it is also the “Achilles’ heel” of hemodialysis.1-3 There are currently three main forms of permanent dialysis vascular access, all of which have their benefits and disadvantages.4 Arteriovenous fistu...

An aqueous solution containing photosynthetic reaction centers (RCs), membrane scaffold proteins (MSPs), phospholipids, and single-walled carbon nanotubes (SWCNTs) solubilized with the surfactant sodium cholate (SC) reversibly self-assembles into a highly ordered structure upon dialysis of the latter. The resulting structure is photoelectrochemically active and consists of 4-nm-thick lipid bila...

BACKGROUND Intradialytic hypotension (IDH) is common and is associated with increased morbidity and mortality in chronic hemodialysis patients. A higher dialysis 'dose' may generate transient intradialytic osmotic gradients, predisposing to intracellular fluid shifts and resulting in hypotension. STUDY DESIGN We performed a post hoc analysis of the HEMO study, a multicenter trial that randomi...

Background: Hemodialysis is still the most common renal replacement therapy (RRT) modality in end stage renal disease patients (ESRD), the first problem to be faced when choosing hemodialysis for patients with ESRD is the vascular access, dia¬lysis delivery should be adequate not only to improve quality of life but also to prolong sur¬vival, quality of life adjusted for life expectancy defined ...