Understanding DNA replication initiation is essential to Background: understand the mis-regulation of replication seen in cancer and other human disorders. DNA replication initiates from DNA replication origins. In eukaryotes, replication is dependent on cell cycle kinases which function during S phase. Dbf4-dependent kinase (DDK) and cyclin-dependent kinase (CDK) act to phosphorylate the DNA h...

PURPOSE The specific mechanisms by which peer passengers increase teen drivers' crash risk are not completely understood. We aimed to provide insight on the two primary hypothesized mechanisms, distraction and promotion of risk-taking behavior, for male and female teen drivers and further for select driver-passenger gender combinations. METHODS From the National Motor Vehicle Crash Causation ...

Understanding DNA replication initiation is essential to Background: understand the mis-regulation of replication seen in cancer and other human disorders. DNA replication initiates from DNA replication origins. In eukaryotes, replication is dependent on cell cycle kinases which function during S phase. Dbf4-dependent kinase (DDK) and cyclin-dependent kinase (CDK) act to phosphorylate the DNA h...

Understanding DNA replication initiation is essential to Background: understand the mis-regulation of replication seen in cancer and other human disorders. DNA replication initiates from DNA replication origins. In eukaryotes, replication is dependent on cell cycle kinases which function during S phase. Dbf4-dependent kinase (DDK) and cyclin-dependent kinase (CDK) act to phosphorylate the DNA h...

There exist the close relationships between technology standards and patented technology licensing. Whether a technology standard contains a specific patented technology solution or not, there is always a patented technology licensing implied: patented technology licensing is a prerequisite for the existence and development of technology standards, and technology standards create a good many of...

Medical condition can negatively effect the capacity to drive safely (1). Thus, in the EU (2) North America (1) and Australia (3), the licensing authorities have imposed certain restrictions or conditions to the concession of driving licenses to persons with particular medical conditions; that is, they are permitted to drive in certain circumstances. In some cases, the conditions or restriction...