To improve the convergence properties of 'embedding' distance geometry, a new approach was developed by combining the distance-geometry methodology with a genetic algorithm. This new approach is called DG-OMEGA (DG omega, optimised metric matrix embedding by genetic algorithms). The genetic algorithm was used to combine well-defined parts of individual structures generated by the distance-geome...

The limitation of using low electron doses in non-destructive cryo-electron tomography of biological specimens can be partially offset via averaging of aligned and structurally homogeneous subsets present in tomograms. This type of sub-volume averaging is especially challenging when multiple species are present. Here, we tackle the problem of conformational separation and alignment with a "coll...

We present two sets of tunings that are broadly applicable to conformer searches of isolated molecules using a genetic algorithm (GA). In order to find the most efficient tunings for the GA, a second GA--a meta-genetic algorithm--was used to tune the first genetic algorithm to reliably find the already known a priori correct answer with minimum computational resources. It is shown that these tu...

an elliptical tank cross-section is formulated to explore and optimization method, based on a real-coded genetic algorithm to enhance the roll stability limit of a tank vehicle. a shape genetic algorithm optimization problem is applied to minimize the overturning moment imposed on the vehicle due to c.g. height of the liquid load, and lateral acceleration and cargo load shift . the minimization...

 This paper present unequal-sized facilities layout solutions generated by a genetic search program named LADEGA (Layout Design using a Genetic Algorithm). The generalized quadratic assignment problem requiring pre-determined distance and material flow matrices as the input data and the continuous plane model employing a dynamic distance measure and a material flow matrix are discussed. Computa...

Organizations expose to financial risk that can lead to bankruptcy and loss of business is increased nowadays. This may leads to discontinuity in operations, increased legal fees, administrative costs and other indirect costs. Accordingly, the purpose of this study was to predict the financial crisis of Tehran Stock Exchange using neural network and genetic algorithm. This research is descripti...

there are many indices for measuring property rights (pr) security. they may be classified into two groups: subjective proxies and objective proxies. most of the proxies are subjective. one contribution of this paper is introducing a new approach for measuring government expenditures devoted to pr protection. calculating physical capital within the introduced new approach is another contributio...

We present an efficient algorithm for maintaining the boundary and surface area of protein molecules as they undergo conformational changes. We also describe a robust implementation of the algorithm and report on experimental results with our implementation on proteins with hundreds of residues. Our work extends and combines two previous results: (i) controlled perturbation for static molecular...

This paper deals with multi-period project portfolio selection problem. In this problem, the available budget is invested on the best portfolio of projects in each period such that the net profit is maximized. We also consider more realistic assumptions to cover wider range of applications than those reported in previous studies. A novel mathematical model is presented to solve the problem, con...