The goal of this work was the research chondroitin sulfate prophylactic action on glutathione system state in rat blood serum during acute joint inflammation. performed white non-linear pubertal males weighting 160-240 grams compliance to all general ethical principles animal research. All animals were divided four experimental groups. first group – control: injected with 0,1 ml 0,9 % NaCl solu...

Caffeine is an alkaloid with a stimulant effect in the body. It can interfere in transmissions based on acetylcholine, epinephrine, norepinephrine, serotonin, dopamine and glutamate. Clinical studies indicate that it can be involved in the slowing of Alzheimer disease pathology and some other effects. The effects are not well understood. In the present work, we focused on the question whether c...

OBJECTIVES To develop a novel and automated assay determining plasma thiol/disulphide homeostasis, which consists of thiol-disulphide exchanges. DESIGN AND METHODS Native thiol and total thiol concentrations were synchronously measured as a paired test. In the first vessel, the amount of native thiol groups was measured by a modified Ellman reagent. At the parallel run, first, dynamic disulph...

iv Swedish summary v List of publications vi List of abbreviations viii 1. Introduction 1 1.1. Infectious diseases 1 1.2. Vector-borne infectious diseases 2 1.2.1. Malaria 2 1.2.2. Dengue 3 1.2.3. Other severe mosquito-borne diseases 4 1.3. Vectors 4 1.3.1. Mosquitoes as disease-vectors 5 1.3.2. Anopheles mosquitoes 5 1.3.3. Aedes mosquitoes 6 1.4. Vector control 7 1.4.1. Insecticid...

BACKGROUND/AIM To evaluate acetylcholinesterase (AChE) inhibitory activity and antioxidant capacity of the major molecule from Salvia sp., rosmarinic acid, as a drug candidate molecule for treatment of Alzheimer disease (AD). MATERIALS AND METHODS The AChE inhibitory activity of different extracts from Salvia trichoclada, Salvia verticillata, and Salvia fruticosa was determined by the Ellman ...

An electrospray ionization/mass spectrometry (ESI/MS)-based assay for the determination of acetylcholinesterase (AChE)-inhibiting activity in snake venom was developed. It allows the direct monitoring of the natural AChE substrate acetylcholine (AC) and the respective product choline. The assay scheme was employed in the screening for neurotoxic activity in fractions of the venom of Bothrops mo...

Introduction: Surgery of inferior turbinates is a divisive subject. Surgical management includes functional and invasive procedures. There is currently no consensus on the most effective technique. Radiofrequency ablation is one of numerous interventions available for the treatment of nasal opstruction secondary to inferior turbinate hypertrophy. The goals of inferior turbinate surgery include ...

In many countries, people are becoming more concerned about pesticide residues which are present in or on food and feed products. For this reason, several methods have been developed to monitor the pesticide residue levels in food samples. In this study, a bioactive paper-based sensor was developed for detection of acetylcholinesterase (AChE) inhibitors including organophosphate and carbamate p...