millions of diarrheal disease is made by enterotoxigenic e. coli (etec) each year, specifically in developing countries. in the pathogenesis of etec infections, the first phase is sticking of the bacterium to the minute intestinal epithelium, as a result of colonization factors (cfs) mediation and subsequently generate enterotoxins. these cfs in accordance with their structure are diverged into...

The development of a solid-phase microtiter radioimmunoassay blocking test to detect serum antibody to Escherichia coli heat-labile enterotoxin is described. The assay is easy to perform and quantitate, and it is sensitive and specific.