Tumor lysis syndrome is an oncologic emergency that usually occurs after chemotherapy in patients with hematologic malignancies. Tumor lysis syndrome is rare in cases of solid tumors, especially when it occurs spontaneously. Herein, we present a case of spontaneous tumor lysis syndrome in a 55-year-old woman who presented with dyspnea and was found to have extensive metastatic small cell lung c...

Localized prostate cancer and polycythemia vera (PV) are rare, and can be difficult to distinguish from bone marrow metastatic prostate cancer. The present study describes a case of prostate cancer occurring with PV. Magnetic resonance imaging revealed diffusely inhomogeneous bone marrow of the pelvis and a localized prostatic mass. The bone marrow biopsy indicated erythrocytosis and leukocytos...

ABSTRACT: To determine the association between ocular abnormalities and hematologic findings in Ehrlichia canis-infected dogs, 120 dogs suspected of canine ehrlichiosis were studied. All patients subjected to rapid serologic diagnostic test for canis, diagnosis was confirmed by quantitative PCR. PCR-positive underwent ophthalmologic examination a hemogram grouped into with thrombocytopenia anem...

A 27-year-old womanwas admitted for further examination of thrombocytopenia. Symptomswere absent, but physical examination demonstrated hepatosplenomegaly without neurological abnormalities. Bone marrow examination revealed many Gaucher cells, and glucocerebrosidase activity from cultured skin fibroblasts was markedly reduced. A 1448C (L444P) mutation was detected on one allele of the glucocere...

Numerical and structural chromosomal abnormalities are common in hematological malignancies. Near-triploidy (58-80 chromosomes) is a numerical abnormality observed in 3% of adult cases of acute lymphoblastic leukemia. Near-triploidy is rare in myeloid lineage hematologic malignancies and compared to near-triploidy in lymphoid malignancies, near-triploidy in myeloid malignancies is associated wi...

Among the hematologic malignancies, the clinical and biologic significance of chromosome abnormalities have been most extensively studied in the acute leukemias and chronic myelogenous leukemia (CML). Clonal chromosome abnormalities are now identified in essentially all cases of CML and in most cases of acute nonlymphoblastic leukemia (ANLL) and acute lymphoblastic leukemia (ALL). In the acute ...

Objective: Myelodysplastic syndrome (MDS) represents one of the most frequent and serious hematologic diseases among the elderly. Chromosomal abnormalities have been detected in 23%–78% patients with MDS. We analyzed the cytogenetics of elderly MDS patients in Turkey. Materials and Methods: Data on patients (>65 years old) diagnosed with primary MDS from 2011 to 2013 were retrospectively collec...

background: cornus mas l, an olive-shaped red-colored single-seeded fruit, is used in traditional medicine in different parts of europe and asia. objectives: in the present study, 40 male wistar rats were randomly divided into five groups, and the effects of 21 days of intraperitoneally (ip) administration of 50, 200 and 400 mg/kg body weight of c. mas hydro-methanolic extract on the rats hemat...

Hyperleukocytosis is a hematologic crisis caused by excessive proliferation of leukemic cells and has relatively high early mortality due to series severe complications. Therefore, prompt effective intervention required. Leukapheresis performed using apheresis equipment separate leukocytes from peripheral blood, at the same time returns autologous plasma, platelets erythrocytes patient, applied...

Secondary erythrocytosis in cyanotic congenital heart disease (CCHD) is a compensatory response to chronic hypoxia which should be managed with caution. CCHD patients, who have compensated erythrocytosis but do not manifest significant neurologic symptoms, may experience secondary life-threatening complications such as stroke in case of inappropriate phlebotomy. This study reports a young man w...