A 38-year-old man with a metastatic gonadotropin-secreting tumor of unknown primary origin presented with both clinical and biochemical findings of hyperthyroidism in association with markedly increased concentrations of human choriogonadotropin (hCG) in plasma. After chemotherapy, the concentrations of both hCG and free thyroxin decreased and the patient became euthyroid. We discuss the rare o...

Background Hyperthyroidism in elderly patients is not to be underevaluated, since it is characterized in such an age range by particular clinical and prognostic features, surgery is the principal treatment of hyperthyroidism, even if therapy and percutaneous alcoholization may play an alternative role in some cases. However the surgical risk may be high in elderly because the presence of comorb...

Relatively few studies have been made of the influence of the thyroid gland on the development and growth of tumors. Lerman (15) stated that the thyroid does not greatly influence the onset and growth of either experimental or human cancer, but Rawson (17) recently cited some experimental and clinical observations which suggest that hyperthyroidism may inhibit, while hypothyroidism may enhance,...

Iodine in the form of Lugol's iodine is commonly prescribed for the treatment of goitre. Eighteen patients, who had positive history of ingestion of iodine are described. Some of the patients had hyperthyroidism when seen while others had thyrotoxicosis like symptoms after taking iodine. Hyperthyroidism was confirmed clinically, radio-isotopically and by response to treatment. Iodine was incrim...

In subclinical hyperthyroidism, thyroid-stimulating hormone (TSH) levels are suppressed below normal range but serum-free thyroxine and free triiodothyronine levels are within normal range. The clinical manifestations can be highly variable and patients mostly remain undiagnosed. Sinus tachycardia, atrial premature beats and atrial fibrillation are the reported tachyarrhythmias in such patients...

Graves' disease is a common autoimmune disorder in women in fertile ages. The hyperthyroidism is caused by generation of TSH-receptor activating antibodies. In pregnancy both the antibodies and the antithyroid medication given to the mother pass the placenta and affect the foetal thyroid gland. Thyroid function should be controlled not only in the mother with Graves' hyperthyroidism but also in...

Radioiodine therapy is the safest, simplest, least expensive and most effective method for treatment of hyperthyroidism. The method employed in this research was a systematic bibliographic review, in which only valid studies or the clinically detailed enough open-labeled studies using validated scales were used. Iodine-131 (I-131) acts by the destructive effect of short-range beta radiation on ...

To investigate the status of the Na+ concentrations [Na+]i, K+ concentrations [K+]i and ionic fluxes in red cells of human subjects with abnormal thyroid function, we measured the Na(+)-K+ pump activity as well as Na(+)-K+ cotransport (CoT), Na(+)-Li+ countertransport (CTT) and Na+ passive permeability in erythrocytes of 37 normal subjects, 19 untreated hyperthyroid patients, 12 treated hyperth...