INTRODUCTION Previous studies have shown that there is a probability of seizure even with therapeutic doses of tramadol. Yet, no accurate data exist regarding this problem in Iran. Therefore, the present study aimed to evaluate the prevalence of tramadol consumption in patients with first seizure referred to the emergency department (ED). METHODS In the present retrospective one-year cross-se...

The seizure prediction problem has been addressed by many researchers from very different fields for more than three decades. The vision of an implantable seizure prediction device may become reality now: the first clinical study of such a device has been realized very recently and other realizations are not far behind. Despite promising first results, however, up to now there is no method allo...

Abstract Background Febrile seizure (FS) is the most common childhood seizures which occur in 2-5% of children. Studies about association between iron deficiency and febrile seizure have shown contradictory results. The purpose of this study was to compare the iron status of children with first febrile seizure and healthy control group. Materials and Methods In an analytic case-control ...

OBJECTIVE The Quality Standards Subcommittee of the American Academy of Neurology develops practice parameters as strategies for patient care based on analysis of evidence. For this practice parameter the authors reviewed available evidence relevant to evaluating adults presenting with an apparent unprovoked first seizure. METHODS Relevant questions were defined and addressed by multiple sear...

BACKGROUND AND PURPOSE To investigate the duration of seizures and its relationship to seizure type, epilepsy syndrome, and seizure clustering. METHODS We examined 1,251 seizures from 152 patients who underwent video-electrocorticographic monitoring with subdural electrodes. Their seizure duration, seizure types, epilepsy syndromes, and seizure clusters were analyzed. RESULTS The median sei...

OBJECTIVE Prediction of a recurrent febrile seizure during subsequent episodes of fever. DESIGN Study of the data of the temperatures, seizure recurrences, and baseline patient characteristics that were collected at a randomized placebo controlled trial of ibuprofen syrup to prevent febrile seizure recurrences. SETTING Two pediatric hospitals in the Netherlands. PATIENTS A total of 230 ch...

BACKGROUND Although epilepsy affects most patients with tuberous sclerosis complex (TSC), little is known about the natural history of epilepsy in this genetic disease. METHODS A retrospective chart review of all patients with TSC seen between January 2002 and October 2008. Charts were reviewed for a history of infantile spasms (IS), seizure other than IS, refractory epilepsy, Lennox-Gastaut ...

PURPOSE We examined the incidence of seizures following ischemic stroke in a community-based sample. METHODS All subjects with incident ischemic strokes in the Framingham Original and Offspring cohorts between 1982 and 2003 were identified and followed for up to 20 years to determine incidence of seizures. Seizure-type was based on the 2010 International League Against Epilepsy (ILAE) classif...

OBJECTIVE Genetically tractable fruit flies have been used for decades to study seizure disorders. However, there is a paucity of data specifically correlating fly and human seizure phenotypes. We have previously shown that mutation of orthologous PRICKLE genes from flies to humans produce seizures. This study aimed to determine whether the prickle-mediated seizure phenotypes in flies closely p...