Abstract Background: Transpupillary thermotherapy is a new treatment for subfoveal choroidal neovascularization which needs further evaluation. This study was aimed to evaluate the efficacy of transpupillary thermotherapy on regression of occult subfoveal choroidal neovascularization with or without pigment epithelial detachment in patients with age-related macular degeneration. Methods: In a ...

During development, neural crest cells migrate dorsolaterally through the skin and differentiate into pigment-producing melanocytes as they reach epidermis. Although well-characterized, these stages of melanocyte differentiation have not been defined at a global transcript level. By analyzing developmental neonatal mouse with single-cell RNA sequencing, we built high quality dataset (n=821) dur...

Background: Nowadays, the rapid recovery of skin lesions and functional return are among the goals of researchers. The skin is the first defensive barrier against microorganisms in the body and its failure causes infection to spread in all systems of the body. By taking into account the contradictory results of previous studies on the impact of phototherapy on wound healing and also the conside...

The occurrence of fluorescent, pigmented inclusion bodies in muscle, nerve, and other non-dividing cell lines has been known since the turn of the century. These pigments, variously known as age pigments, lipofuscin, or abnutzungspig-mente (wear and tear pigments), have been subjected to numerous histochemical and histo-logical studies. Little has been firmly established, however, regarding the...

This study aims to reconcile industrially suitable strains of higher red pigment producing Monascus purpureus MPA5 and Monacolin K ruber MRA7, were tried fuse for development increased efficacy targeted secondary metabolites production. The optimum concentration protoplast mixture was standardized, before the fusion experiment. effective observed with solution 30 % PEG 6000, CaCl2.2H2O (0.01 M)...

they form juxtaposed pointillistic colour centres which, to our eyes, create the stimulus of the colour green (the same principle is used in many neo-impressionist paintings). One further special feature of this structurally coloured system, and possibly the reason it evolved, is that only the blue colour component is significantly linearly polarised; linear polarisation is sometimes used for i...

Background: There is a growing demand for mass production of shikalkin (a natural pigment consisted of shikonin and alkannin) due to its increasing applications in cosmetics, pharmaceutical and nutrition industries. The root of Iranian Arnebia euchroma produces shikalkin. The promising capability of this plant for shikalkin production has already been demonstrated in cell culture studies. Obje...

The present study is designed to evaluate the application of a simple method for rapid identification of Malassezia furfur among other Malassezia spp. based on production of a brownish-red pigment and its diffusion into the medium containing L-tryptophan as a sigle source of nitrogen.  91 strains of Malassezia (20% M. furfur, 2% M. sympodialis, 5% M. obtosa and 73% M. globosa) isolated from ski...

BACKGROUND Cells in the trabecular meshwork (TM), the tissue responsible for draining aqueous humor out of the eye, are known to be highly phagocytic. Phagocytic function in TM cells is thought to play an important role in the normal functioning of the outflow pathway. Dysfunction of phagocytosis could lead to abnormalities of outflow resistance and increased intraocular pressure (IOP). However...