The Automated Neuropsychological Assessment Metrics (ANAM) is a computerized neuropsychological assessment battery that has demonstrated utility in a variety of clinical populations including multiple sclerosis, systemic lupus erythematosus, Parkinson's disease, acquired brain injury, migraine headaches, and Alzheimer's disease. This study utilized selected tests from the ANAM General Neuropsyc...

The importance of evaluating effort in neuropsychological assessments has been widely acknowledged, but measuring effort in the context of dementia remains challenging due to the impact of dementia severity on effort measure scores. Two embedded measures have been developed for the repeatable battery for the assessment of neuropsychological status (RBANS; Randolph, C., Tierney, M. C., Mohr, E.,...

BACKGROUND In the 24-month MS-STAT phase 2 trial, we showed that high-dose simvastatin significantly reduced the annualised rate of whole brain atrophy in patients with secondary progressive multiple sclerosis (SPMS). We now describe the results of the MS-STAT cognitive substudy, in which we investigated the treatment effect on cognitive, neuropsychiatric, and health-related quality-of-life (HR...

Mild cognitive impairment (MCI) may affect multiple neuropsychological domains. While amnestic MCI is associated with Alzheimer's disease, patterns of brain pathology in non-amnestic subtypes have been less studied. Twenty-three patients with attention/executive MCI (a/e MCI), seen at a university-based memory clinic, and 23 normal controls, matched according to age, gender, and education, were...

Previous research with older adults suggests that the frontal lobes and the medial temporal lobes play an important role in recognition memory. The goal of this study was to investigate the impact of high/low frontal lobe and medial temporal lobe status in younger adults’ recognition memory performance. Twenty-four college-aged women completed a neuropsychological battery and a recognition memo...

OBJECTIVE To determine whether plasma homocysteine (Hcy) levels are associated with clinical characteristics, neuropsychological and psychiatric manifestations and cardiovascular comorbidity in patients with Parkinson disease (PD). BACKGROUND Elevated Hcy levels are linked to atherosclerosis, vascular disease, depression, and dementia. Patients with PD treated with L-dopa have been shown to h...

AIMS This study examined the frontal lobe cognitive function and the mental state among patients with different types of alcohol dependence according to Lesch's typology. METHODS The frontal assessment battery (FAB) and the mini-mental status examination (MMSE) were given to 170 patients with alcoholism from a Brazilian outpatient service classified by Lesch's typology and to 40 non-alcoholic...

This paper provides a preliminary battery assessment mechanism to address the hypothetical ECO-America EV Challenge. Several battery parameters are discussed in relation to pack needs, in addition to vehicle and environmental considerations. An evaluation method is provided, with a vision based on success and a metric for battery evaluation for the ECO-America Challenge. Five in-house testing p...

In the process of battery system design and operation, accurate battery modelling is a key factor. Generally speaking, the electric characteristics of a given battery cell are necessary for a designer to build an equivalent circuit model. The equivalent circuit design entails the creation of both the sizing of components used in the circuit and the topology. So, it is very hard to build an accu...