نتایج جستجو برای: fungal allergen
تعداد نتایج: 65062 فیلتر نتایج به سال:
Background and purpose: Âsthma is a chronic disease that is classified in two types, Âllergic and non-Âllergic. Ïn allergic type allergens such as fungi induce asthmatic reactions. Ünlike the most common allergens such as mite, pollen and chemicals, fungal spore, as an allergen is ubiquitous and present in different seasons. The aim of this study was the determine the incidence of ÏgË to comm...
BACKGROUND Conflicting results have been reported in studies of predictive factors for airway responsiveness to allergens during bronchial challenges. OBJECTIVE The aim of this study was to assess determinants of airway responsiveness to 3 different allergens during standardized bronchial challenges. METHODS Data were collected from asthmatic patients who participated in allergen challenge ...
Purpose: To develop chitosan/alginate microparticles for the mucosal delivery of allergen from dust mite (Dermatophagoides pteronyssinus). Methods: Chitosan/alginate microparticles were prepared by ionotropic gelation. The effects of polymer content, crosslinking agent, and preparation method on the physicochemical characteristics of the microparticles as well as their in vitro cytotoxicity wer...
In this issue of the Journal of the Chinese Medical Association, Liang et al describe a study that evaluates the skin test (Tori Ltd, Tokyo, Japan) and specific IgE antibodies (ImmunoCAP system; Pharmacia, Uppsala, Sweden), which are designed to identify mold allergy. Five fungal antigens (Candida, Alternaria, Aspergillus, Cladosporium and Penicillium) were included in this study. With the stea...
BACKGROUND The mechanism underlying severe asthma with fungal sensitization (SAFS) is unknown. IL-33 is important in fungus-induced asthma exacerbations, but its role in fungal sensitization is unexplored. OBJECTIVE We sought to determine whether fungal sensitization in children with severe therapy-resistant asthma is mediated by IL-33. METHODS Eighty-two children (median age, 11.7 years; 6...
CONTEXT The diagnostic algorithm for human allergic disease involves confirmation of sensitization by detection of allergen-specific immunoglobulin E (IgE) antibody in individuals suspected of having allergic disease because of a history of allergic symptoms after known allergen exposure. Previous studies showed wide disparity among clinically reported allergen-specific IgE levels from differen...
BACKGROUND Asthma-associated morbidity is rising, especially in inner city children. OBJECTIVE We evaluated the allergen sensitivities, allergen exposures, and associated morbidity for participants in the Inner City Asthma Study. We also determined geographic variations of indoor allergen levels. METHODS Nine hundred thirty-seven inner city children 5 to 11 years old with moderate to severe...
Repeated low-dose allergen challenge increases airway hyperresponsiveness in atopic asthmatics. However, it is not known whether low-dose allergen challenge increases airway inflammation. Eight atopic asthmatics were enrolled in a controlled, cross-over study to evaluate the effect and time course of repeated low-dose allergen challenge on airway inflammation and hyperresponsiveness. The dose o...
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