conclusions expression levels of 1,426 genes were significantly up-regulated in the mutant compared to wt. furthermore, 301 genes were down-regulated with false discovery rates (fdr) of < 0.001 and absolute value of log2 ratio of ≥ 1. results a total of 4,182,944 and 4,182,021 clean tags were obtained from the wt and a nonpathogenic mutant stain (bct89), respectively, and 10,410 differentially ...

conclusions in this experimental study, for the first time in iran the expression and purification of this recombinant protein was done successfully. this recombinant protein could be used as a vaccine candidate and diagnostic purpose in subsequent investigations. results the highest expression of the cytochrome p450 cyp141 protein was obtained by the addition of 1 mm of isopropyl β-d-1-thiogal...

nf-κb pathway is a link between inflammation and cancer and is involved in cellular responses to different stimuli. gastrointestinal lumen is exposed to many inflammatory agents such as foods, free radicals and bacterial or viral antigens. the aim of the present study was to evaluate the possible role of nf-κb1in gastric adenocarcinoma. to detect the relative level of nf-κb1transcript, total rn...

the siberian sturgeon (acipenser baerii) is an economically important species. sturgeon stockassessment during fingerling production is considered to be one of the most difficult phases ofhatchery rearing. the present study investigated the expression of growth hormone (gh)mrna in unfertilized eggs, fertilized eggs, eyed eggs (2 day before hatching), non-viable eggsand newly-hatched siberian st...

aim : to evaluate the effect of active t. gondii tachyzoites and its products on the gene expression level of ifn-yr1 and ifn-yr2 in a murine model.   background : many studies have shown that the parasite toxoplasma gondii utilizes different mechanisms to inhibit the function of ifn-?, but the parasite effect on the function of ifn-yr1 and ifn-yr2 is still unclear. patients and methods : toxop...

introduction: calcium/calmodulin-dependent protein kinase ii (camkii) is highly expressed in the hippocampus, which has a pivotal role in reward-related memories and morphine dependence. methods: in the present study, morphine tolerance was induced in male wistar rats by 7 days repeated morphine injections once daily, and then gene expression profile of α-isoform of camkii (camkiiα) in the hipp...

objective(s): to explore the correlation between expression patterns and functions of mir-383 and ldha in hepatocellular cancer (hcc). materials and methods: we detected the expression of mir-383 and ldha in 30 hcc tissues and their matched adjacent normal tissues using qrt-pcr. then we performed mtt assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...

gastric cardia adenocarcinoma (gca)is one of the few malignancies with unexplained reasons that have increased sharply in developed countries. the purpose of this review was to determine the pathways in gca to identify new biomarker. so by comparing gene expression in gca group with normal control identified important pathways. gene expression data were extracted from the beforehand investigati...